Can Devstral Small 1.1 run on AMD Instinct MI250X 128GB?

YES — Runs Great

S87Excellent
Estimated from fit model

Devstral Small 1.1 needs ~30.8 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~183 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 30.8 GB, 183.3 tok/s, Runs well
30.8 GB required128.0 GB available
24% VRAM used

Fit status

Runs well

Decode

183.3 tok/s

TTFT

1056 ms

Safe context

131K

Memory

30.8 GB / 128.0 GB

Memory breakdown

Weights14.6 GB
KV Cache2.4 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsDevstral Small 1.1 on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 183.3 tok/s decode · 1.1s TTFT (warm) · 458 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatSRuns well183.3 tok/s576 ms131K
CodingSRuns well183.3 tok/s1056 ms131K
Agentic CodingSRuns well183.3 tok/s1536 ms131K
ReasoningSRuns well183.3 tok/s1248 ms131K
RAGSRuns well183.3 tok/s1921 ms131K

Quantization options

How Devstral Small 1.1 (24B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
9.4 GB
LowA78
Q3_K_S
3
11.8 GB
LowA78
NVFP4
4
13.4 GB
MediumA78
Q4_K_M
4
14.6 GB
MediumA78
Q5_K_M
5
17.3 GB
HighA78
Q6_K
6
19.7 GB
HighA79
Q8_0
8
25.7 GB
Very HighA79
F16Best for your GPU
16
49.2 GB
MaximumA83

Get started

Copy-paste commands to run Devstral Small 1.1 on your machine.

Run

lms load Devstral-Small-2507 && lms server start

Your hardware

More models your AMD Instinct MI250X 128GB can run

ModelParamsGradeDecodeCapabilities
MistralDevstral 2 123B Instruct123BS36.2 tok/s
AlibabaQwen3-Coder 30B A3B Instruct30.5BS377.4 tok/s
AlibabaQwen 3.5 27B27BS163.7 tok/s
AlibabaQwen 3.6 27B27BS102 tok/s
AlibabaQwen 3.5 122B A10B122BS100.3 tok/s

Frequently asked questions

Can AMD Instinct MI250X 128GB run Devstral Small 1.1?

Yes, AMD Instinct MI250X 128GB can run Devstral Small 1.1 with a S grade (Runs well). Expected decode speed: 183.3 tok/s.

How much VRAM does Devstral Small 1.1 need?

Devstral Small 1.1 (24B parameters) requires approximately 30.8 GB of memory with Q4_K_M quantization.

What is the best quantization for Devstral Small 1.1?

The recommended quantization for Devstral Small 1.1 is Q4_K_M, which balances quality and memory efficiency.

What speed will Devstral Small 1.1 run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Devstral Small 1.1 achieves approximately 183.3 tokens per second decode speed with a time-to-first-token of 1056ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Devstral Small 1.1 for coding?

For coding workloads, Devstral Small 1.1 on AMD Instinct MI250X 128GB receives a S grade with 183.3 tok/s and 131K context.

What context window can Devstral Small 1.1 use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Devstral Small 1.1 can safely use up to 131K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GBSee all hardware for Devstral Small 1.1
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