Can Qwen 2.5 Coder 32B run on AMD Instinct MI250X 128GB?

YES — Runs Great

A76Great

Estimated from fit model

Qwen 2.5 Coder 32B needs ~37.1 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~138 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 37.1 GB, 138.1 tok/s, Runs well

37.1 GB required128.0 GB available

29% VRAM used

Fit status

Runs well

Decode

138.1 tok/s

TTFT

1402 ms

Safe context

131K

Memory

37.1 GB / 128.0 GB

Memory breakdown

Weights19.5 GB

KV Cache3.9 GB

Runtime0.9 GB

Headroom12.8 GB

See how fast it feels

See how fast it feelsQwen 2.5 Coder 32B on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 138.1 tok/s decode · 1.4s TTFT (warm) · 345 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	138.1 tok/s	765 ms	131K
Coding	A	Runs well	138.1 tok/s	1402 ms	131K
Agentic Coding	A	Runs well	138.1 tok/s	2039 ms	131K
Reasoning	A	Runs well	127.9 tok/s	1789 ms	131K
RAG	A	Runs well	138.1 tok/s	2549 ms	131K

Quantization options

How Qwen 2.5 Coder 32B (32B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	12.5 GB	Low	B66
Q3_K_S	3	15.7 GB	Low	B67
NVFP4	4	17.9 GB	Medium	B67
Q4_K_M	4	19.5 GB	Medium	B67
Q5_K_M	5	23.0 GB	High	B67
Q6_K	6	26.2 GB	High	B68
Q8_0	8	34.2 GB	Very High	B69
F16Best for your GPU	16	65.6 GB	Maximum	A74

Get started

Copy-paste commands to run Qwen 2.5 Coder 32B on your machine.

Run

ollama run qwen2.5-coder

Your hardware

More models your AMD Instinct MI250X 128GB can run

Model	Params	Grade	Decode
Devstral 2 123B Instruct	123B	S	36.2 tok/s
Qwen 3.5 122B A10B	122B	S	100.3 tok/s
Qwen 3.6 35B A3B	35B	S	317.2 tok/s
Qwen 3.5 35B A3B	35B	S	344.9 tok/s
Mistral Small 4 119B	119B	S	108.8 tok/s

Frequently asked questions

Can AMD Instinct MI250X 128GB run Qwen 2.5 Coder 32B?

Yes, AMD Instinct MI250X 128GB can run Qwen 2.5 Coder 32B with a A grade (Runs well). Expected decode speed: 138.1 tok/s.

How much VRAM does Qwen 2.5 Coder 32B need?

Qwen 2.5 Coder 32B (32B parameters) requires approximately 37.1 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 2.5 Coder 32B?

The recommended quantization for Qwen 2.5 Coder 32B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 2.5 Coder 32B run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Qwen 2.5 Coder 32B achieves approximately 138.1 tokens per second decode speed with a time-to-first-token of 1402ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Qwen 2.5 Coder 32B for coding?

For coding workloads, Qwen 2.5 Coder 32B on AMD Instinct MI250X 128GB receives a A grade with 138.1 tok/s and 131K context.

What context window can Qwen 2.5 Coder 32B use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Qwen 2.5 Coder 32B can safely use up to 131K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GB See all hardware for Qwen 2.5 Coder 32B

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