Will It Run AI

Can Mixtral 8x22B run on NVIDIA DGX Spark 128GB?

YES — With Offload

B58Good
Estimated from fit model

Mixtral 8x22B needs ~103.4 GB VRAM. NVIDIA DGX Spark 128GB has 108.8 GB. With Q4_K_M quantization, expect ~4 tok/s.

Runtime: llama.cppCapacity: OffloadBandwidth: LowStack: StandardBottleneck: Memory bandwidth
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 103.4 GB, 4.0 tok/s, Runs with offload
103.4 GB required108.8 GB available
95% VRAM used

Fit status

Runs with offload

Decode

4.0 tok/s

TTFT

48916 ms

Safe context

41K

Memory

103.4 GB / 108.8 GB

Memory breakdown

Weights86.0 GB
KV Cache3.4 GB
Runtime0.9 GB
Headroom13.1 GB

See how fast it feels

See how fast it feelsMixtral 8x22B on NVIDIA DGX Spark 128GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 4.0 tok/s decode · 48.9s TTFT (warm) · 10 tok/s prefill

What limits this setup

The model fits in shared memory, but shared-memory bandwidth is now the real limiter.

Fit does not mean dedicated-VRAM speed

Unified or shared memory can make a model technically fit, but sustained tokens per second may still trail a discrete high-bandwidth GPU with less total memory.

Very little memory headroom

You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.

Shared-memory contention still exists

The OS, browser, and inference runtime all compete for the same physical memory pool, so real-world headroom is less forgiving than raw capacity suggests.

Best improvement path

Prioritize bandwidth, not only capacity

If this workload feels slow, the next useful step is often a GPU tier with materially faster memory bandwidth rather than only a small bump in capacity.

Buy headroom, not only minimum fit

A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatBTight fit4.0 tok/s26681 ms41K
CodingBRuns with offload4.0 tok/s48916 ms41K
Agentic CodingBRuns with offload4.0 tok/s71150 ms41K
ReasoningBRuns with offload4.0 tok/s57809 ms41K
RAGBRuns with offload4.0 tok/s88937 ms41K

Quantization options

How Mixtral 8x22B (141B params) fits at each quantization level on NVIDIA DGX Spark 128GB (92.2 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
55.0 GB
LowB61
Q3_K_SBest for your GPU
3
69.1 GB
LowB61
NVFP4
4
79.0 GB
MediumF0
Q4_K_M
4
86.0 GB
MediumF0
Q5_K_M
5
101.5 GB
HighF0
Q6_K
6
115.6 GB
HighF0
Q8_0
8
150.9 GB
Very HighF0
F16
16
289.0 GB
MaximumF0

Get started

Copy-paste commands to run Mixtral 8x22B on your machine.

Run

ollama run mixtral:8x22b

Opciones de mejora

Hardware que ejecuta bien Mixtral 8x22B

Frequently asked questions

Can NVIDIA DGX Spark 128GB run Mixtral 8x22B?

Yes, NVIDIA DGX Spark 128GB can run Mixtral 8x22B with a B grade (Runs with offload). Expected decode speed: 4.0 tok/s.

How much VRAM does Mixtral 8x22B need?

Mixtral 8x22B (141B parameters) requires approximately 103.4 GB of memory with Q4_K_M quantization.

What is the best quantization for Mixtral 8x22B?

The recommended quantization for Mixtral 8x22B is Q4_K_M, which balances quality and memory efficiency.

What speed will Mixtral 8x22B run at on NVIDIA DGX Spark 128GB?

On NVIDIA DGX Spark 128GB, Mixtral 8x22B achieves approximately 4.0 tokens per second decode speed with a time-to-first-token of 48916ms using Q4_K_M quantization.

Can NVIDIA DGX Spark 128GB run Mixtral 8x22B for coding?

For coding workloads, Mixtral 8x22B on NVIDIA DGX Spark 128GB receives a B grade with 4.0 tok/s and 41K context.

What context window can Mixtral 8x22B use on NVIDIA DGX Spark 128GB?

On NVIDIA DGX Spark 128GB, Mixtral 8x22B can safely use up to 41K tokens of context. The model's official context limit is 66K, but available memory constrains the safe maximum.

What should I upgrade first if Mixtral 8x22B feels slow on NVIDIA DGX Spark 128GB?

Prioritize bandwidth, not only capacity. If this workload feels slow, the next useful step is often a GPU tier with materially faster memory bandwidth rather than only a small bump in capacity.

Is unified memory on NVIDIA DGX Spark 128GB as fast as VRAM for Mixtral 8x22B?

Not always. NVIDIA DGX Spark 128GB can often fit larger models thanks to unified memory, but a discrete GPU with dedicated high-bandwidth VRAM may still decode faster once the model fits. For this combination, the important distinction is capacity versus sustained throughput.

See all results for NVIDIA DGX Spark 128GBSee all hardware for Mixtral 8x22B
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