Will It Run AI

Can Hermes 4.3 36B run on AMD Instinct MI60 32GB?

YES — Tight Fit

C49Usable
Estimated from fit model

Hermes 4.3 36B needs ~30.3 GB VRAM. AMD Instinct MI60 32GB has 32.0 GB. With Q4_K_M quantization, expect ~23 tok/s.

Runtime: llama.cppCapacity: TightBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 30.3 GB, 22.8 tok/s, Tight fit
30.3 GB required32.0 GB available
95% VRAM used

Fit status

Tight fit

Decode

22.8 tok/s

TTFT

8473 ms

Safe context

23K

Memory

30.3 GB / 32.0 GB

Memory breakdown

Weights22.0 GB
KV Cache4.2 GB
Runtime0.9 GB
Headroom3.2 GB

See how fast it feels

See how fast it feelsHermes 4.3 36B on AMD Instinct MI60 32GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 22.8 tok/s decode · 8.5s TTFT (warm) · 57 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Very little memory headroom

You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.

Best improvement path

Buy headroom, not only minimum fit

A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatCTight fit22.8 tok/s4622 ms23K
CodingCTight fit22.8 tok/s8473 ms23K
Agentic CodingDRuns with offload (needs ~1.6 GB host RAM)14.6 tok/s19249 ms23K
ReasoningCTight fit22.8 tok/s10014 ms23K
RAGDRuns with offload (needs ~1.6 GB host RAM)14.6 tok/s24061 ms23K

Quantization options

How Hermes 4.3 36B (36B params) fits at each quantization level on AMD Instinct MI60 32GB (32.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
14.0 GB
LowC48
Q3_K_S
3
17.6 GB
LowC49
NVFP4
4
20.2 GB
MediumC49
Q4_K_MBest for your GPU
4
22.0 GB
MediumC49
Q5_K_M
5
25.9 GB
HighF0
Q6_K
6
29.5 GB
HighF0
Q8_0
8
38.5 GB
Very HighF0
F16
16
73.8 GB
MaximumF0

Get started

Copy-paste commands to run Hermes 4.3 36B on your machine.

Run

lms load hf-nousresearch--hermes-4-3-36b-gguf && lms server start

Opciones de mejora

Hardware que ejecuta bien Hermes 4.3 36B

Radeon Pro W7900 48GBOpción económica
48 GB VRAM (+16)
C
Añade margen de memoria para más contexto y para que el modelo envejezca mejor.23.2 tok/s decodificación

Añade margen de memoria para más contexto y para que el modelo envejezca mejor.

~$3,999 MSRP

Radeon PRO W7900 DS 48GBMejor relación calidad-precio
48 GB VRAM (+16)
C
Añade margen de memoria para más contexto y para que el modelo envejezca mejor.23.2 tok/s decodificación

Añade margen de memoria para más contexto y para que el modelo envejezca mejor.

~$3,999 MSRP

AMD Instinct MI210 64GBMejora AMD
64 GB VRAM (+32)1638 GB/s (+614)
C
Sube la velocidad estimada de decodificación alrededor de un 122%.50.7 tok/s decodificación

Sube la velocidad estimada de decodificación alrededor de un 122%.

Añade margen de memoria para más contexto y para que el modelo envejezca mejor.

~$10,000 MSRP

Frequently asked questions

Can AMD Instinct MI60 32GB run Hermes 4.3 36B?

Yes, AMD Instinct MI60 32GB can run Hermes 4.3 36B with a C grade (Tight fit). Expected decode speed: 22.8 tok/s.

How much VRAM does Hermes 4.3 36B need?

Hermes 4.3 36B (36B parameters) requires approximately 30.3 GB of memory with Q4_K_M quantization.

What is the best quantization for Hermes 4.3 36B?

The recommended quantization for Hermes 4.3 36B is Q4_K_M, which balances quality and memory efficiency.

What speed will Hermes 4.3 36B run at on AMD Instinct MI60 32GB?

On AMD Instinct MI60 32GB, Hermes 4.3 36B achieves approximately 22.8 tokens per second decode speed with a time-to-first-token of 8473ms using Q4_K_M quantization.

Can AMD Instinct MI60 32GB run Hermes 4.3 36B for coding?

For coding workloads, Hermes 4.3 36B on AMD Instinct MI60 32GB receives a C grade with 22.8 tok/s and 23K context.

What context window can Hermes 4.3 36B use on AMD Instinct MI60 32GB?

On AMD Instinct MI60 32GB, Hermes 4.3 36B can safely use up to 23K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

What should I upgrade first if Hermes 4.3 36B feels slow on AMD Instinct MI60 32GB?

Buy headroom, not only minimum fit. A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

See all results for AMD Instinct MI60 32GBSee all hardware for Hermes 4.3 36B
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