Can Devstral Small 2 24B Instruct run on AMD Instinct MI325X 256GB?

YES — Runs Great

S87Excellent
Estimated from fit model

Devstral Small 2 24B Instruct needs ~43.6 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~322 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 43.6 GB, 321.6 tok/s, Runs well
43.6 GB required256.0 GB available
17% VRAM used

Fit status

Runs well

Decode

321.6 tok/s

TTFT

602 ms

Safe context

256K

Memory

43.6 GB / 256.0 GB

Memory breakdown

Weights14.6 GB
KV Cache2.4 GB
Runtime0.9 GB
Headroom25.6 GB

See how fast it feels

See how fast it feelsDevstral Small 2 24B Instruct on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 321.6 tok/s decode · 602ms TTFT (warm) · 804 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatSRuns well321.6 tok/s350 ms256K
CodingSRuns well321.6 tok/s602 ms256K
Agentic CodingSRuns well321.6 tok/s876 ms256K
ReasoningSRuns well321.6 tok/s711 ms256K
RAGSRuns well321.6 tok/s1094 ms256K

Inference speed

Devstral Small 2 24B Instruct inference speed — tokens per second by GPU & Mac

Estimated decode speed (tokens/sec) for Devstral Small 2 24B Instruct at Q4_K_M across popular GPUs and Apple Silicon, using the fastest local runtime per device. Fastest is RTX 5090 32GB at ~88 tok/s. Speed is memory-bandwidth bound, so cards that fit the whole model in VRAM run far faster than ones that offload to system RAM.

GPU / MacMemoryQuantSpeed (tok/s)Fits?
NVIDIARTX 5090 32GB
32 GBQ4_K_M88.2Fits
NVIDIARTX 4090 24GB
24 GBQ4_K_M56.3Tight
RX 7900 XTX 24GB
24 GBQ4_K_M50.8Tight
NVIDIARTX 3090 24GB
24 GBQ4_K_M48.1Tight
Mac Studio M3 Ultra 256GB
256 GBQ4_K_M40.9Fits
MacBook Pro M4 Max 128GB
128 GBQ4_K_M36.8Fits
MacBook Pro M4 Max 64GB
64 GBQ4_K_M36.8Fits
Mac Studio M2 Ultra 128GB
128 GBQ4_K_M34.1Fits
Mac Studio M1 Ultra 128GB
128 GBQ4_K_M32.3Fits
MacBook Pro M4 Pro 48GB
48 GBQ4_K_M23.2Fits
NVIDIARTX 4080 Super 16GB
16 GBQ4_K_M21.3Too big
MacBook Pro M3 Max 64GB
64 GBQ4_K_M17.6Fits
MacBook Pro M1 Max 64GB
64 GBQ4_K_M16.2Fits
NVIDIARTX 4070 12GB
12 GBQ4_K_M7.5Too big
NVIDIARTX 3060 12GB
12 GBQ4_K_M4.7Too big
NVIDIARTX 4060 8GB
8 GBQ4_K_M2.2Too big

Estimates for single-stream decoding at Q4_K_M; real tokens/sec varies with prompt length, context, batch size, and runtime build. Prompt processing (prefill) is faster than the decode figures shown here.

Quantization options

How Devstral Small 2 24B Instruct (24B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
9.4 GB
LowA77
Q3_K_S
3
11.8 GB
LowA77
NVFP4
4
13.4 GB
MediumA78
Q4_K_M
4
14.6 GB
MediumA78
Q5_K_M
5
17.3 GB
HighA78
Q6_K
6
19.7 GB
HighA78
Q8_0
8
25.7 GB
Very HighA79
F16Best for your GPU
16
49.2 GB
MaximumA81

Get started

Copy-paste commands to run Devstral Small 2 24B Instruct on your machine.

Run

ollama run devstral-small-2

Your hardware

More models your AMD Instinct MI325X 256GB can run

ModelParamsGradeDecodeCapabilities
AlibabaQwen 3.5 397B A17B397BA39.2 tok/s
MistralDevstral 2 123B Instruct123BS63.5 tok/s
AlibabaQwen3-Coder 30B A3B Instruct30.5BS662.3 tok/s
AlibabaQwen 3.5 27B27BS287.2 tok/s
AlibabaQwen 3.6 27B27BS179 tok/s

Frequently asked questions

Can AMD Instinct MI325X 256GB run Devstral Small 2 24B Instruct?

Yes, AMD Instinct MI325X 256GB can run Devstral Small 2 24B Instruct with a S grade (Runs well). Expected decode speed: 321.6 tok/s.

How much VRAM does Devstral Small 2 24B Instruct need?

Devstral Small 2 24B Instruct (24B parameters) requires approximately 43.6 GB of memory with Q4_K_M quantization.

What is the best quantization for Devstral Small 2 24B Instruct?

The recommended quantization for Devstral Small 2 24B Instruct is Q4_K_M, which balances quality and memory efficiency.

What speed will Devstral Small 2 24B Instruct run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Devstral Small 2 24B Instruct achieves approximately 321.6 tokens per second decode speed with a time-to-first-token of 602ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Devstral Small 2 24B Instruct for coding?

For coding workloads, Devstral Small 2 24B Instruct on AMD Instinct MI325X 256GB receives a S grade with 321.6 tok/s and 256K context.

What context window can Devstral Small 2 24B Instruct use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Devstral Small 2 24B Instruct can safely use up to 256K tokens of context. The model's official context limit is 256K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GBSee all hardware for Devstral Small 2 24B Instruct
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