Can Codestral 2 25.08 run on AMD Instinct MI250 128GB?

YES — Runs Great

A81Great
Estimated from fit model

Codestral 2 25.08 needs ~29.6 GB VRAM. AMD Instinct MI250 128GB has 128.0 GB. With Q4_K_M quantization, expect ~164 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 29.6 GB, 163.8 tok/s, Runs well
29.6 GB required128.0 GB available
23% VRAM used

Fit status

Runs well

Decode

163.8 tok/s

TTFT

1182 ms

Safe context

256K

Memory

29.6 GB / 128.0 GB

Memory breakdown

Weights13.4 GB
KV Cache2.4 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsCodestral 2 25.08 on AMD Instinct MI250 128GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 163.8 tok/s decode · 1.2s TTFT (warm) · 410 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatARuns well163.8 tok/s644 ms256K
CodingARuns well163.8 tok/s1182 ms256K
Agentic CodingARuns well163.8 tok/s1719 ms256K
ReasoningARuns well163.8 tok/s1396 ms256K
RAGARuns well163.8 tok/s2148 ms256K

Quantization options

How Codestral 2 25.08 (22B params) fits at each quantization level on AMD Instinct MI250 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
8.6 GB
LowA73
Q3_K_S
3
10.8 GB
LowA73
NVFP4
4
12.3 GB
MediumA73
Q4_K_M
4
13.4 GB
MediumA73
Q5_K_M
5
15.8 GB
HighA73
Q6_K
6
18.0 GB
HighA73
Q8_0
8
23.5 GB
Very HighA74
F16Best for your GPU
16
45.1 GB
MaximumA77

Get started

Copy-paste commands to run Codestral 2 25.08 on your machine.

Run

lms load codestral-2508 && lms server start

Your hardware

More models your AMD Instinct MI250 128GB can run

ModelParamsGradeDecodeCapabilities
MistralDevstral 2 123B Instruct123BS31.5 tok/s
AlibabaQwen3-Coder 30B A3B Instruct30.5BS329 tok/s
AlibabaQwen 3.5 27B27BS142.7 tok/s
AlibabaQwen 3.6 27B27BS88.9 tok/s
AlibabaQwen 3.5 122B A10B122BS87.5 tok/s

Frequently asked questions

Can AMD Instinct MI250 128GB run Codestral 2 25.08?

Yes, AMD Instinct MI250 128GB can run Codestral 2 25.08 with a A grade (Runs well). Expected decode speed: 163.8 tok/s.

How much VRAM does Codestral 2 25.08 need?

Codestral 2 25.08 (22B parameters) requires approximately 29.6 GB of memory with Q4_K_M quantization.

What is the best quantization for Codestral 2 25.08?

The recommended quantization for Codestral 2 25.08 is Q4_K_M, which balances quality and memory efficiency.

What speed will Codestral 2 25.08 run at on AMD Instinct MI250 128GB?

On AMD Instinct MI250 128GB, Codestral 2 25.08 achieves approximately 163.8 tokens per second decode speed with a time-to-first-token of 1182ms using Q4_K_M quantization.

Can AMD Instinct MI250 128GB run Codestral 2 25.08 for coding?

For coding workloads, Codestral 2 25.08 on AMD Instinct MI250 128GB receives a A grade with 163.8 tok/s and 256K context.

What context window can Codestral 2 25.08 use on AMD Instinct MI250 128GB?

On AMD Instinct MI250 128GB, Codestral 2 25.08 can safely use up to 256K tokens of context. The model's official context limit is 256K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250 128GBSee all hardware for Codestral 2 25.08
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