Can Nemotron Nano 8B run on AMD Instinct MI250X 128GB?

YES — Runs Great

A80Great

Estimated from fit model

Nemotron Nano 8B needs ~20.5 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~112 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 20.5 GB, 112.0 tok/s, Runs well

20.5 GB required128.0 GB available

16% VRAM used

Fit status

Runs well

Decode

112.0 tok/s

TTFT

1729 ms

Safe context

131K

Memory

20.5 GB / 128.0 GB

Memory breakdown

Weights4.9 GB

KV Cache2.0 GB

Runtime0.9 GB

Headroom12.8 GB

See how fast it feels

See how fast it feelsNemotron Nano 8B on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 112.0 tok/s decode · 1.7s TTFT (warm) · 280 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	112.0 tok/s	943 ms	131K
Coding	A	Runs well	112.0 tok/s	1729 ms	131K
Agentic Coding	A	Runs well	112.0 tok/s	2514 ms	131K
Reasoning	A	Runs well	112.0 tok/s	2043 ms	131K
RAG	A	Runs well	112.0 tok/s	3143 ms	131K

Quantization options

How Nemotron Nano 8B (8B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	3.1 GB	Low	A73
Q3_K_S	3	3.9 GB	Low	A73
NVFP4	4

Get started

Copy-paste commands to run Nemotron Nano 8B on your machine.

Run

lms load Llama-3.1-Nemotron-Nano-8B-v1 && lms server start

Your hardware

More models your AMD Instinct MI250X 128GB can run

Model	Params	Grade	Decode	Capabilities
Devstral 2 123B Instruct	123B	S	36.2 tok/s
Qwen3-Coder 30B A3B Instruct	30.5B	S

Frequently asked questions

Can AMD Instinct MI250X 128GB run Nemotron Nano 8B?

Yes, AMD Instinct MI250X 128GB can run Nemotron Nano 8B with a A grade (Runs well). Expected decode speed: 112.0 tok/s.

How much VRAM does Nemotron Nano 8B need?

Nemotron Nano 8B (8B parameters) requires approximately 20.5 GB of memory with Q4_K_M quantization.

What is the best quantization for Nemotron Nano 8B?

The recommended quantization for Nemotron Nano 8B is Q4_K_M, which balances quality and memory efficiency.

What speed will Nemotron Nano 8B run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Nemotron Nano 8B achieves approximately 112.0 tokens per second decode speed with a time-to-first-token of 1729ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Nemotron Nano 8B for coding?

For coding workloads, Nemotron Nano 8B on AMD Instinct MI250X 128GB receives a A grade with 112.0 tok/s and 131K context.

What context window can Nemotron Nano 8B use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Nemotron Nano 8B can safely use up to 131K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GB See all hardware for Nemotron Nano 8B

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