Will It Run AI

Can BaichuanMed OCR 72B i1 run on AMD Instinct MI250X 128GB?

YES — Runs Great

C51Usable
Estimated from fit model

BaichuanMed OCR 72B i1 needs ~66.1 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~57 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 66.1 GB, 56.8 tok/s, Runs well
66.1 GB required128.0 GB available
52% VRAM used

Fit status

Runs well

Decode

56.8 tok/s

TTFT

3407 ms

Safe context

133K

Memory

66.1 GB / 128.0 GB

Memory breakdown

Weights43.9 GB
KV Cache8.4 GB
Runtime0.9 GB
Headroom12.8 GB

See how fast it feels

See how fast it feelsBaichuanMed OCR 72B i1 on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API. When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed. Key benefits of running locally: - Full privacy: your prompts never leave your machine - No per-token cost or rate limits - Works offline once the model is downloaded - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb: Model size Q4 (4-bit) Q8 (8-bit) FP16 7B params ~4.3 GB ~7.5 GB ~14 GB 13B params ~7.9 GB ~13.9 GB ~26 GB 70B params ~42.7 GB ~74.9 GB ~140 GB Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 56.8 tok/s decode · 3.4s TTFT (warm) · 142 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatCRuns well56.8 tok/s1858 ms133K
CodingCRuns well56.8 tok/s3407 ms133K
Agentic CodingCRuns well56.8 tok/s4955 ms133K
ReasoningCRuns well56.8 tok/s4026 ms133K
RAGCRuns well56.8 tok/s6194 ms133K

Quantization options

How BaichuanMed OCR 72B i1 (72B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
28.1 GB
LowD40
Q3_K_S
3
35.3 GB
LowC41
NVFP4
4
40.3 GB
MediumC42
Q4_K_M
4
43.9 GB
MediumC43
Q5_K_M
5
51.8 GB
HighC44
Q6_K
6
59.0 GB
HighC45
Q8_0Best for your GPU
8
77.0 GB
Very HighC47
F16
16
147.6 GB
MaximumF0

Get started

Copy-paste commands to run BaichuanMed OCR 72B i1 on your machine.

Run

lms load hf-mradermacher--baichuanmed-ocr-72b-i1-gguf && lms server start

升级选项

能流畅运行 BaichuanMed OCR 72B i1 的硬件

Frequently asked questions

Can AMD Instinct MI250X 128GB run BaichuanMed OCR 72B i1?

Yes, AMD Instinct MI250X 128GB can run BaichuanMed OCR 72B i1 with a C grade (Runs well). Expected decode speed: 56.8 tok/s.

How much VRAM does BaichuanMed OCR 72B i1 need?

BaichuanMed OCR 72B i1 (72B parameters) requires approximately 66.1 GB of memory with Q4_K_M quantization.

What is the best quantization for BaichuanMed OCR 72B i1?

The recommended quantization for BaichuanMed OCR 72B i1 is Q4_K_M, which balances quality and memory efficiency.

What speed will BaichuanMed OCR 72B i1 run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, BaichuanMed OCR 72B i1 achieves approximately 56.8 tokens per second decode speed with a time-to-first-token of 3407ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run BaichuanMed OCR 72B i1 for coding?

For coding workloads, BaichuanMed OCR 72B i1 on AMD Instinct MI250X 128GB receives a C grade with 56.8 tok/s and 133K context.

What context window can BaichuanMed OCR 72B i1 use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, BaichuanMed OCR 72B i1 can safely use up to 133K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GBSee all hardware for BaichuanMed OCR 72B i1
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