Can Qwen 2.5 32B run on AMD Instinct MI325X 256GB?

YES — Runs Great

A80Great

Estimated from fit model

Qwen 2.5 32B needs ~49.9 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~224 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 49.9 GB, 242.3 tok/s, Runs well

49.9 GB required256.0 GB available

19% VRAM used

Fit status

Runs well

Decode

242.3 tok/s

TTFT

799 ms

Safe context

131K

Memory

49.9 GB / 256.0 GB

Memory breakdown

Weights19.5 GB

KV Cache3.9 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsQwen 2.5 32B on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 242.3 tok/s decode · 799ms TTFT (warm) · 606 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	224.4 tok/s	471 ms	131K
Coding	A	Runs well	224.4 tok/s	863 ms	131K
Agentic Coding	A	Runs well	224.4 tok/s	1255 ms	131K
Reasoning	A	Runs well	224.4 tok/s	1020 ms	131K
RAG	A	Runs well	224.4 tok/s	1569 ms	131K

Quantization options

How Qwen 2.5 32B (32B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	12.5 GB	Low	B70
Q3_K_S	3	15.7 GB	Low	A70
NVFP4	4	17.9 GB	Medium	A70
Q4_K_M	4	19.5 GB	Medium	A70
Q5_K_M	5	23.0 GB	High	A71
Q6_K	6	26.2 GB	High	A71
Q8_0	8	34.2 GB	Very High	A72
F16Best for your GPU	16	65.6 GB	Maximum	A74

Get started

Copy-paste commands to run Qwen 2.5 32B on your machine.

Run

ollama run qwen2.5

Your hardware

More models your AMD Instinct MI325X 256GB can run

Model	Params	Grade	Decode
Qwen 3.5 397B A17B	397B	A	39.2 tok/s
Devstral 2 123B Instruct	123B	S	63.5 tok/s
Qwen 3.5 122B A10B	122B	S	176.1 tok/s
DeepSeek V4 Flash	284B	S	94.4 tok/s
Qwen 3.6 35B A3B	35B	S	556.6 tok/s

Frequently asked questions

Can AMD Instinct MI325X 256GB run Qwen 2.5 32B?

Yes, AMD Instinct MI325X 256GB can run Qwen 2.5 32B with a A grade (Runs well). Expected decode speed: 224.4 tok/s.

How much VRAM does Qwen 2.5 32B need?

Qwen 2.5 32B (32B parameters) requires approximately 49.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 2.5 32B?

The recommended quantization for Qwen 2.5 32B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 2.5 32B run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Qwen 2.5 32B achieves approximately 224.4 tokens per second decode speed with a time-to-first-token of 863ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Qwen 2.5 32B for coding?

For coding workloads, Qwen 2.5 32B on AMD Instinct MI325X 256GB receives a A grade with 224.4 tok/s and 131K context.

What context window can Qwen 2.5 32B use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Qwen 2.5 32B can safely use up to 131K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for Qwen 2.5 32B

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