Can BaichuanMed OCR 72B i1 run on AMD Instinct MI325X 256GB?

YES — Runs Great

C48Usable

Estimated from fit model

BaichuanMed OCR 72B i1 needs ~78.9 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~100 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 78.9 GB, 99.7 tok/s, Runs well

78.9 GB required256.0 GB available

31% VRAM used

Fit status

Runs well

Decode

99.7 tok/s

TTFT

1941 ms

Safe context

352K

Memory

78.9 GB / 256.0 GB

Memory breakdown

Weights43.9 GB

KV Cache8.4 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsBaichuanMed OCR 72B i1 on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 99.7 tok/s decode · 1.9s TTFT (warm) · 249 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	99.7 tok/s	1059 ms	352K
Coding	C	Runs well	99.7 tok/s	1941 ms	352K
Agentic Coding	C	Runs well	99.7 tok/s	2824 ms	352K
Reasoning	C	Runs well	99.7 tok/s	2294 ms	352K
RAG	C	Runs well	99.7 tok/s	3530 ms	352K

Quantization options

How BaichuanMed OCR 72B i1 (72B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	28.1 GB	Low	D37
Q3_K_S	3	35.3 GB	Low	D38
NVFP4	4	40.3 GB	Medium	D38
Q4_K_M	4	43.9 GB	Medium	D39
Q5_K_M	5	51.8 GB	High	D39
Q6_K	6	59.0 GB	High	D40
Q8_0	8	77.0 GB	Very High	C41
F16Best for your GPU	16	147.6 GB	Maximum	C47

Get started

Copy-paste commands to run BaichuanMed OCR 72B i1 on your machine.

Run

lms load hf-mradermacher--baichuanmed-ocr-72b-i1-gguf && lms server start

Frequently asked questions

Can AMD Instinct MI325X 256GB run BaichuanMed OCR 72B i1?

Yes, AMD Instinct MI325X 256GB can run BaichuanMed OCR 72B i1 with a C grade (Runs well). Expected decode speed: 99.7 tok/s.

How much VRAM does BaichuanMed OCR 72B i1 need?

BaichuanMed OCR 72B i1 (72B parameters) requires approximately 78.9 GB of memory with Q4_K_M quantization.

What is the best quantization for BaichuanMed OCR 72B i1?

The recommended quantization for BaichuanMed OCR 72B i1 is Q4_K_M, which balances quality and memory efficiency.

What speed will BaichuanMed OCR 72B i1 run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, BaichuanMed OCR 72B i1 achieves approximately 99.7 tokens per second decode speed with a time-to-first-token of 1941ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run BaichuanMed OCR 72B i1 for coding?

For coding workloads, BaichuanMed OCR 72B i1 on AMD Instinct MI325X 256GB receives a C grade with 99.7 tok/s and 352K context.

What context window can BaichuanMed OCR 72B i1 use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, BaichuanMed OCR 72B i1 can safely use up to 352K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for BaichuanMed OCR 72B i1

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