Can InternLM 20B run on AMD Instinct MI325X 256GB?

YES — Runs Great

C55Usable

Estimated from fit model

InternLM 20B needs ~59.2 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q5_K_M quantization, expect ~280 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q5_K_M (High quality) — 59.2 GB, 280.0 tok/s, Runs well

59.2 GB required256.0 GB available

23% VRAM used

Fit status

Runs well

Decode

280.0 tok/s

TTFT

691 ms

Safe context

Memory

59.2 GB / 256.0 GB

Memory breakdown

Weights14.4 GB

KV Cache18.3 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsInternLM 20B on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 280.0 tok/s decode · 691ms TTFT (warm) · 700 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	280.0 tok/s	377 ms	8K
Coding	C	Runs well	280.0 tok/s	691 ms	8K
Agentic Coding	B	Runs well	280.0 tok/s	1006 ms	8K
Reasoning	C	Runs well	280.0 tok/s	817 ms	8K
RAG	B	Runs well	280.0 tok/s	1257 ms	8K

Quantization options

How InternLM 20B (20B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	7.8 GB	Low	C44
Q3_K_S	3	9.8 GB	Low	C44
NVFP4	4	11.2 GB	Medium	C44
Q4_K_M	4	12.2 GB	Medium	C44
Q5_K_M	5	14.4 GB	High	C44
Q6_K	6	16.4 GB	High	C44
Q8_0	8	21.4 GB	Very High	C45
F16Best for your GPU	16	41.0 GB	Maximum	C46

Get started

Copy-paste commands to run InternLM 20B on your machine.

Run

docker run --rm -it ghcr.io/ggerganov/llama.cpp:full \
  --hf-repo "internlm/internlm2_5-20b-chat" \
  --hf-file "internlm2_5-20b-chat-Q5_K_M.gguf" \
  -c 4096 -ngl 99

Frequently asked questions

Can AMD Instinct MI325X 256GB run InternLM 20B?

Yes, AMD Instinct MI325X 256GB can run InternLM 20B with a C grade (Runs well). Expected decode speed: 280.0 tok/s.

How much VRAM does InternLM 20B need?

InternLM 20B (20B parameters) requires approximately 59.2 GB of memory with Q5_K_M quantization.

What is the best quantization for InternLM 20B?

The recommended quantization for InternLM 20B is Q5_K_M, which balances quality and memory efficiency.

What speed will InternLM 20B run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, InternLM 20B achieves approximately 280.0 tokens per second decode speed with a time-to-first-token of 691ms using Q5_K_M quantization.

Can AMD Instinct MI325X 256GB run InternLM 20B for coding?

For coding workloads, InternLM 20B on AMD Instinct MI325X 256GB receives a C grade with 280.0 tok/s and 8K context.

What context window can InternLM 20B use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, InternLM 20B can safely use up to 8K tokens of context. The model's official context limit is 8K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for InternLM 20B

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