Can GPT-OSS 20B run on Quadro RTX 8000 48GB?

YES — Runs Great

S90Excellent
Estimated from fit model

GPT-OSS 20B needs ~21.3 GB VRAM. Quadro RTX 8000 48GB has 48.0 GB. With Q4_K_M quantization, expect ~89 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: MediumStack: BasicBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 21.3 GB, 89.0 tok/s, Runs well
21.3 GB required48.0 GB available
44% VRAM used

Fit status

Runs well

Decode

89.0 tok/s

TTFT

2175 ms

Safe context

128K

Memory

21.3 GB / 48.0 GB

Memory breakdown

Weights12.8 GB
KV Cache2.4 GB
Runtime1.2 GB
Headroom4.8 GB

See how fast it feels

See how fast it feelsGPT-OSS 20B on Quadro RTX 8000 48GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 89.0 tok/s decode · 2.2s TTFT (warm) · 223 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

Older PCIe generation

PCIe 3.0 is workable, but it compounds the penalty when you offload heavily or try to scale across multiple cards.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatSRuns well89.0 tok/s1186 ms128K
CodingSRuns well89.0 tok/s2175 ms128K
Agentic CodingSRuns well89.0 tok/s3164 ms128K
ReasoningSRuns well89.0 tok/s2570 ms128K
RAGSRuns well89.0 tok/s3954 ms128K

Inference speed

GPT-OSS 20B inference speed — tokens per second by GPU & Mac

Estimated decode speed (tokens/sec) for GPT-OSS 20B at Q4_K_M across popular GPUs and Apple Silicon, using the fastest local runtime per device. Fastest is RTX 5090 32GB at ~231 tok/s. Speed is memory-bandwidth bound, so cards that fit the whole model in VRAM run far faster than ones that offload to system RAM.

GPU / MacMemoryQuantSpeed (tok/s)Fits?
NVIDIARTX 5090 32GB
32 GBQ4_K_M230.5Fits
NVIDIARTX 4090 24GB
24 GBQ4_K_M147.1Fits
RX 7900 XTX 24GB
24 GBQ4_K_M132.7Fits
NVIDIARTX 3090 24GB
24 GBQ4_K_M125.8Fits
Mac Studio M3 Ultra 256GB
256 GBQ4_K_M106.9Fits
Mac Studio M2 Ultra 128GB
128 GBQ4_K_M89.1Fits
Mac Studio M1 Ultra 128GB
128 GBQ4_K_M84.5Fits
NVIDIARTX 4080 Super 16GB
16 GBQ4_K_M68.2Heavy offload
MacBook Pro M4 Max 128GB
128 GBQ4_K_M66.0Fits
MacBook Pro M4 Max 64GB
64 GBQ4_K_M66.0Fits
MacBook Pro M3 Max 64GB
64 GBQ4_K_M46.1Fits
MacBook Pro M1 Max 64GB
64 GBQ4_K_M42.2Fits
MacBook Pro M4 Pro 48GB
48 GBQ4_K_M40.4Fits
NVIDIARTX 4070 12GB
12 GBQ4_K_M24.2Too big
NVIDIARTX 3060 12GB
12 GBQ4_K_M15.2Too big
NVIDIARTX 4060 8GB
8 GBQ4_K_M5.7Too big

Estimates for single-stream decoding at Q4_K_M; real tokens/sec varies with prompt length, context, batch size, and runtime build. Prompt processing (prefill) is faster than the decode figures shown here.

Quantization options

How GPT-OSS 20B (21B params) fits at each quantization level on Quadro RTX 8000 48GB (48.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
8.2 GB
LowA81
Q3_K_S
3
10.3 GB
LowA82
NVFP4
4
11.8 GB
MediumA82
Q4_K_M
4
12.8 GB
MediumA82
Q5_K_M
5
15.1 GB
HighA83
Q6_K
6
17.2 GB
HighA84
Q8_0Best for your GPU
8
22.5 GB
Very HighS85
F16
16
43.1 GB
MaximumF0

Get started

Copy-paste commands to run GPT-OSS 20B on your machine.

Run

ollama run gpt-oss

Your hardware

More models your Quadro RTX 8000 48GB can run

ModelParamsGradeDecodeCapabilities
AlibabaQwen3-Coder 30B A3B Instruct30.5BS70.1 tok/s
AlibabaQwen 3.5 27B27BS30.4 tok/s
AlibabaQwen 3.6 27B27BS30.5 tok/s
AlibabaQwen 3.6 35B A3B35BS58.9 tok/s
AlibabaQwen3-VL 30B A3B Instruct30BS72.5 tok/s

Frequently asked questions

Can Quadro RTX 8000 48GB run GPT-OSS 20B?

Yes, Quadro RTX 8000 48GB can run GPT-OSS 20B with a S grade (Runs well). Expected decode speed: 89.0 tok/s.

How much VRAM does GPT-OSS 20B need?

GPT-OSS 20B (21B parameters) requires approximately 21.3 GB of memory with Q4_K_M quantization.

What is the best quantization for GPT-OSS 20B?

The recommended quantization for GPT-OSS 20B is Q4_K_M, which balances quality and memory efficiency.

What speed will GPT-OSS 20B run at on Quadro RTX 8000 48GB?

On Quadro RTX 8000 48GB, GPT-OSS 20B achieves approximately 89.0 tokens per second decode speed with a time-to-first-token of 2175ms using Q4_K_M quantization.

Can Quadro RTX 8000 48GB run GPT-OSS 20B for coding?

For coding workloads, GPT-OSS 20B on Quadro RTX 8000 48GB receives a S grade with 89.0 tok/s and 128K context.

What context window can GPT-OSS 20B use on Quadro RTX 8000 48GB?

On Quadro RTX 8000 48GB, GPT-OSS 20B can safely use up to 128K tokens of context. The model's official context limit is 128K, but available memory constrains the safe maximum.

See all results for Quadro RTX 8000 48GBSee all hardware for GPT-OSS 20B
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