Can GPT-OSS 20B run on Quadro RTX 6000 24GB?
YES — Runs Great
GPT-OSS 20B needs ~18.9 GB VRAM. Quadro RTX 6000 24GB has 24.0 GB. With Q4_K_M quantization, expect ~89 tok/s.
Operating mode
Choose the run profile you care about
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
89.0 tok/s
TTFT
2175 ms
Safe context
50K
Memory
18.9 GB / 24.0 GB
Memory breakdown
See how fast it feels
What limits this setup
This setup is broadly balanced for this model.
Older PCIe generation
PCIe 3.0 is workable, but it compounds the penalty when you offload heavily or try to scale across multiple cards.
Best improvement path
Performance by workload
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | S | Runs well | 89.0 tok/s | 1186 ms | 50K |
| Coding | S | Runs well | 89.0 tok/s | 2175 ms | 50K |
| Agentic Coding | S | Tight fit | 89.0 tok/s | 3164 ms | 50K |
| Reasoning | S | Runs well | 89.0 tok/s | 2570 ms | 50K |
| RAG | S | Tight fit | 89.0 tok/s | 3954 ms | 50K |
Quantization options
How GPT-OSS 20B (21B params) fits at each quantization level on Quadro RTX 6000 24GB (24.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 8.2 GB | Low | S86 |
Q3_K_S | 3 | 10.3 GB | Low | S88 |
NVFP4 | 4 | 11.8 GB | Medium | S89 |
Q4_K_M | 4 | 12.8 GB | Medium | S89 |
Q5_K_M | 5 | 15.1 GB | High | S88 |
Q6_KBest for your GPU | 6 | 17.2 GB | High | S88 |
Q8_0 | 8 | 22.5 GB | Very High | F0 |
F16 | 16 | 43.1 GB | Maximum | F0 |
Get started
Copy-paste commands to run GPT-OSS 20B on your machine.
Run
ollama run gpt-ossYour hardware
More models your Quadro RTX 6000 24GB can run
| Model | Params | Grade | Decode | Capabilities |
|---|---|---|---|---|
| 30.5B | S | 70.1 tok/s | ||
| 27B | S | 30.4 tok/s | ||
| 27B | S | 30.5 tok/s | ||
| 30B | S | 72.5 tok/s | ||
| 35B | A | 37.9 tok/s |
Frequently asked questions
Can Quadro RTX 6000 24GB run GPT-OSS 20B?
Yes, Quadro RTX 6000 24GB can run GPT-OSS 20B with a S grade (Runs well). Expected decode speed: 89.0 tok/s.
How much VRAM does GPT-OSS 20B need?
GPT-OSS 20B (21B parameters) requires approximately 18.9 GB of memory with Q4_K_M quantization.
What is the best quantization for GPT-OSS 20B?
The recommended quantization for GPT-OSS 20B is Q4_K_M, which balances quality and memory efficiency.
What speed will GPT-OSS 20B run at on Quadro RTX 6000 24GB?
On Quadro RTX 6000 24GB, GPT-OSS 20B achieves approximately 89.0 tokens per second decode speed with a time-to-first-token of 2175ms using Q4_K_M quantization.
Can Quadro RTX 6000 24GB run GPT-OSS 20B for coding?
For coding workloads, GPT-OSS 20B on Quadro RTX 6000 24GB receives a S grade with 89.0 tok/s and 50K context.
What context window can GPT-OSS 20B use on Quadro RTX 6000 24GB?
On Quadro RTX 6000 24GB, GPT-OSS 20B can safely use up to 50K tokens of context. The model's official context limit is 128K, but available memory constrains the safe maximum.
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