Can Mistral Small 4 119B run on AMD Instinct MI325X 256GB?

YES — Runs Great

S91Excellent

Estimated from fit model

Mistral Small 4 119B needs ~104.5 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~191 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 104.5 GB, 190.9 tok/s, Runs well

104.5 GB required256.0 GB available

41% VRAM used

Fit status

Runs well

Decode

190.9 tok/s

TTFT

1014 ms

Safe context

256K

Memory

104.5 GB / 256.0 GB

Memory breakdown

Weights72.6 GB

KV Cache5.4 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsMistral Small 4 119B on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 190.9 tok/s decode · 1.0s TTFT (warm) · 477 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	S	Runs well	190.9 tok/s	553 ms	256K
Coding	S	Runs well	190.9 tok/s	1014 ms	256K
Agentic Coding	S	Runs well	190.9 tok/s	1475 ms	256K
Reasoning	S	Runs well	190.9 tok/s	1198 ms	256K
RAG	S	Runs well	190.9 tok/s	1844 ms	256K

Quantization options

How Mistral Small 4 119B (119B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	46.4 GB	Low	A80
Q3_K_S	3	58.3 GB	Low	A81
NVFP4	4	66.6 GB	Medium	A82
Q4_K_M	4	72.6 GB	Medium	A82
Q5_K_M	5	85.7 GB	High	A83
Q6_K	6	97.6 GB	High	A84
Q8_0Best for your GPU	8	127.3 GB	Very High	S87
F16	16	244.0 GB	Maximum	F0

Get started

Copy-paste commands to run Mistral Small 4 119B on your machine.

Run

lms load Mistral-Small-4-119B-2603 && lms server start

Your hardware

More models your AMD Instinct MI325X 256GB can run

Model	Params	Grade	Decode
Qwen 3.5 397B A17B	397B	A	39.2 tok/s
Devstral 2 123B Instruct	123B	S	63.5 tok/s
Qwen 3.5 122B A10B	122B	S	176.1 tok/s
DeepSeek V4 Flash	284B	S	94.4 tok/s

Frequently asked questions

Can AMD Instinct MI325X 256GB run Mistral Small 4 119B?

Yes, AMD Instinct MI325X 256GB can run Mistral Small 4 119B with a S grade (Runs well). Expected decode speed: 190.9 tok/s.

How much VRAM does Mistral Small 4 119B need?

Mistral Small 4 119B (119B parameters) requires approximately 104.5 GB of memory with Q4_K_M quantization.

What is the best quantization for Mistral Small 4 119B?

The recommended quantization for Mistral Small 4 119B is Q4_K_M, which balances quality and memory efficiency.

What speed will Mistral Small 4 119B run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Mistral Small 4 119B achieves approximately 190.9 tokens per second decode speed with a time-to-first-token of 1014ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Mistral Small 4 119B for coding?

For coding workloads, Mistral Small 4 119B on AMD Instinct MI325X 256GB receives a S grade with 190.9 tok/s and 256K context.

What context window can Mistral Small 4 119B use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Mistral Small 4 119B can safely use up to 256K tokens of context. The model's official context limit is 256K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for Mistral Small 4 119B

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