Will It Run AI

Can Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored run on AMD Instinct MI100 32GB?

YES — With NVFP4

D38Poor
Estimated from fit model

Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored needs ~36.6 GB VRAM. AMD Instinct MI100 32GB has 32.0 GB. With NVFP4 quantization, expect ~18 tok/s.

Runtime: llama.cppCapacity: OffloadBandwidth: HighStack: StandardBottleneck: Host offload
Share:

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored at Q4_K_M needs 39.0 GB — too much for AMD Instinct MI100 32GB (32.0 GB). Runs at NVFP4 (36.6 GB) with medium quality. 3 quantization levels fit.
Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 39.0 GB, exceeds 32.0 GB available
39.0 GB required32.0 GB available
122% VRAM needed

7.0 GB over capacity — needs offload or smaller quantization

Fit status

Too heavy

Decode

13.5 tok/s

TTFT

14364 ms

Safe context

4K

Memory

39.0 GB / 32.0 GB

Offload

20%

Memory breakdown

Weights29.3 GB
KV Cache5.6 GB
Runtime0.9 GB
Headroom3.2 GB

See how fast it feels

With memory offload — actual speed may be lower
See how fast it feelsQwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored on AMD Instinct MI100 32GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 13.5 tok/s decode · 14.4s TTFT (warm) · 34 tok/s prefill

What limits this setup

It fits through host-memory offload, and offload is the main reason performance drops.

CPU or host-memory offload is active

About 10% of the working set spills out of accelerator memory, which usually hurts latency and sustained decode throughput.

Very little memory headroom

You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.

Best improvement path

Remove offload with more accelerator memory

Prioritize a GPU or unified-memory tier that fits the whole model natively. Removing offload usually helps more than small compute gains.

Buy headroom, not only minimum fit

A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.

Increase host RAM if you keep offloading

This setup may need roughly 3.4 GB of extra host RAM just for the offloaded portion, before OS and other tools.

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatDVery compromised (needs ~3.4 GB host RAM)15.8 tok/s6693 ms4K
CodingFToo heavy13.5 tok/s14364 ms4K
Agentic CodingFToo heavy10.2 tok/s27743 ms4K
ReasoningFToo heavy13.5 tok/s16975 ms4K
RAGFToo heavy10.2 tok/s34679 ms4K

Quantization options

How Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored (48B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
18.7 GB
LowC49
Q3_K_SBest for your GPU
3
23.5 GB
LowC48
NVFP4
4
26.9 GB
MediumF0
Q4_K_M
4
29.3 GB
MediumF0
Q5_K_M
5
34.6 GB
HighF0
Q6_K
6
39.4 GB
HighF0
Q8_0
8
51.4 GB
Very HighF0
F16
16
98.4 GB
MaximumF0

Get started

Copy-paste commands to run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored on your machine.

Run

lms load hf-davidau--qwen3-48b-a4b-savant-commander-distill-12x-closed-open-heretic-uncensored-gguf && lms server start

Opciones de mejora

Hardware que ejecuta bien Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored

Frequently asked questions

Can AMD Instinct MI100 32GB run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored?

Yes, AMD Instinct MI100 32GB can run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored at NVFP4 quantization (Very compromised (needs ~3.4 GB host RAM)). The recommended Q4_K_M requires 39.0 GB which exceeds available memory, but at NVFP4 it needs only 36.6 GB. Expected decode speed: 17.6 tok/s.

How much VRAM does Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored need?

Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored (48B parameters) requires approximately 39.0 GB at Q4_K_M quantization. On AMD Instinct MI100 32GB, it fits at NVFP4 using 36.6 GB.

What is the best quantization for Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored?

The recommended quantization is Q4_K_M, but on AMD Instinct MI100 32GB the best fitting quantization is NVFP4, which uses 36.6 GB.

What speed will Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored run at on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored achieves approximately 17.6 tokens per second decode speed with a time-to-first-token of 10987ms using NVFP4 quantization.

Can AMD Instinct MI100 32GB run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored for coding?

For coding workloads, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored on AMD Instinct MI100 32GB receives a F grade with 13.5 tok/s and 4K context.

What context window can Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored use on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored can safely use up to 4K tokens of context at NVFP4 quantization. The model's official context limit is —, but available memory constrains the safe maximum.

What should I upgrade first if Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored feels slow on AMD Instinct MI100 32GB?

Remove offload with more accelerator memory. Prioritize a GPU or unified-memory tier that fits the whole model natively. Removing offload usually helps more than small compute gains.

See all results for AMD Instinct MI100 32GBSee all hardware for Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored
Embed this result

Paste this snippet into any page to show a live fit card.

<iframe src="https://willitrunai.com/embed/hf-davidau--qwen3-48b-a4b-savant-commander-distill-12x-closed-open-heretic-uncensored-gguf-on-instinct-mi100-32gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>

Preview: