Can Qwen 3.5 35B A3B run on AMD Instinct MI100 32GB?

YES — Tight Fit

S95Excellent
Estimated from fit model

Qwen 3.5 35B A3B needs ~26.9 GB VRAM. AMD Instinct MI100 32GB has 32.0 GB. With Q4_K_M quantization, expect ~110 tok/s.

Runtime: llama.cppCapacity: TightBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 26.9 GB, 110.3 tok/s, Tight fit
26.9 GB required32.0 GB available
84% VRAM used

Fit status

Tight fit

Decode

110.3 tok/s

TTFT

1755 ms

Safe context

72K

Memory

26.9 GB / 32.0 GB

Memory breakdown

Weights21.3 GB
KV Cache1.5 GB
Runtime0.9 GB
Headroom3.2 GB

See how fast it feels

See how fast it feelsQwen 3.5 35B A3B on AMD Instinct MI100 32GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 110.3 tok/s decode · 1.8s TTFT (warm) · 276 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatSRuns well110.3 tok/s957 ms72K
CodingSTight fit110.3 tok/s1755 ms72K
Agentic CodingSTight fit110.3 tok/s2553 ms72K
ReasoningSTight fit110.3 tok/s2074 ms72K
RAGSTight fit110.3 tok/s3191 ms72K

Inference speed

Qwen 3.5 35B A3B inference speed — tokens per second by GPU & Mac

Estimated decode speed (tokens/sec) for Qwen 3.5 35B A3B at Q4_K_M across popular GPUs and Apple Silicon, using the fastest local runtime per device. Fastest is RTX 5090 32GB at ~139 tok/s. Speed is memory-bandwidth bound, so cards that fit the whole model in VRAM run far faster than ones that offload to system RAM.

GPU / MacMemoryQuantSpeed (tok/s)Fits?
NVIDIARTX 5090 32GB
32 GBQ4_K_M139.4Tight
Mac Studio M3 Ultra 256GB
256 GBQ4_K_M100.1Fits
Mac Studio M2 Ultra 128GB
128 GBQ4_K_M83.4Fits
Mac Studio M1 Ultra 128GB
128 GBQ4_K_M79.1Fits
NVIDIARTX 4090 24GB
24 GBQ4_K_M71.1Heavy offload
MacBook Pro M4 Max 128GB
128 GBQ4_K_M61.8Fits
MacBook Pro M4 Max 64GB
64 GBQ4_K_M61.8Fits
RX 7900 XTX 24GB
24 GBQ4_K_M60.0Heavy offload
NVIDIARTX 3090 24GB
24 GBQ4_K_M56.9Heavy offload
MacBook Pro M3 Max 64GB
64 GBQ4_K_M47.4Fits
MacBook Pro M1 Max 64GB
64 GBQ4_K_M43.5Fits
MacBook Pro M4 Pro 48GB
48 GBQ4_K_M41.5Tight
NVIDIARTX 4080 Super 16GB
16 GBQ4_K_M25.2Too big
NVIDIARTX 4070 12GB
12 GBQ4_K_M8.8Too big
NVIDIARTX 3060 12GB
12 GBQ4_K_M5.2Too big
NVIDIARTX 4060 8GB
8 GBQ4_K_M4.4Too big

Estimates for single-stream decoding at Q4_K_M; real tokens/sec varies with prompt length, context, batch size, and runtime build. Prompt processing (prefill) is faster than the decode figures shown here.

Quantization options

How Qwen 3.5 35B A3B (35B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
13.7 GB
LowS90
Q3_K_S
3
17.2 GB
LowS91
NVFP4
4
19.6 GB
MediumS91
Q4_K_M
4
21.3 GB
MediumS90
Q5_K_MBest for your GPU
5
25.2 GB
HighS90
Q6_K
6
28.7 GB
HighF0
Q8_0
8
37.5 GB
Very HighF0
F16
16
71.8 GB
MaximumF0

Get started

Copy-paste commands to run Qwen 3.5 35B A3B on your machine.

Run

ollama run qwen3.5:35b-a3b

Frequently asked questions

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B?

Yes, AMD Instinct MI100 32GB can run Qwen 3.5 35B A3B with a S grade (Tight fit). Expected decode speed: 110.3 tok/s.

How much VRAM does Qwen 3.5 35B A3B need?

Qwen 3.5 35B A3B (35B parameters) requires approximately 26.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 3.5 35B A3B?

The recommended quantization for Qwen 3.5 35B A3B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 3.5 35B A3B run at on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B achieves approximately 110.3 tokens per second decode speed with a time-to-first-token of 1755ms using Q4_K_M quantization.

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B for coding?

For coding workloads, Qwen 3.5 35B A3B on AMD Instinct MI100 32GB receives a S grade with 110.3 tok/s and 72K context.

What context window can Qwen 3.5 35B A3B use on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B can safely use up to 72K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI100 32GBSee all hardware for Qwen 3.5 35B A3B
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