Can Qwen 2.5 VL 72B run on RTX PRO 6000 Blackwell Workstation Edition 96GB?

YES — Runs Great

S93Excellent
Estimated from fit model

Qwen 2.5 VL 72B needs ~59.3 GB VRAM. RTX PRO 6000 Blackwell Workstation Edition 96GB has 96.0 GB. With Q4_K_M quantization, expect ~37 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 59.3 GB, 37.3 tok/s, Runs well
59.3 GB required96.0 GB available
62% VRAM used

Fit status

Runs well

Decode

37.3 tok/s

TTFT

5194 ms

Safe context

33K

Memory

59.3 GB / 96.0 GB

Memory breakdown

Weights43.9 GB
KV Cache4.9 GB
Runtime0.9 GB
Headroom9.6 GB

See how fast it feels

See how fast it feelsQwen 2.5 VL 72B on RTX PRO 6000 Blackwell Workstation Edition 96GB
1st promptCold start — includes initialization
>Solve: If a train travels at 60 mph for 2.5 hours, how far does it go?
Let me work through this step by step. Given information: - Speed = 60 mph (miles per hour) - Time = 2.5 hours Formula: Distance = Speed x Time Calculation: Distance = 60 mph x 2.5 h = 150 miles The train travels 150 miles. Double-check: at 60 mph the train covers 60 miles each hour. In half an hour it covers 30 miles. So in 2.5 hours: 60 + 60 + 30 = 150 miles. Confirmed.
2nd promptWarm — model ready, no init overhead
>What if the train stops for 20 minutes halfway?
The stop doesn't change the total distance covered while moving, but it affects total trip time. Breakdown: - First half: 1.25 hours at 60 mph = 75 miles - Stop: 20 minutes (no distance) - Second half: 1.25 hours at 60 mph = 75 miles Total distance: 150 miles (same) Total time: 2.5 h + 0.33 h = 2.83 hours Average speed: 150 / 2.83 = 53 mph The distance stays the same but average speed drops to 53 mph because of the stop.
Estimated: 37.3 tok/s decode · 5.2s TTFT (warm) · 93 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatSRuns well37.3 tok/s2833 ms33K
CodingSRuns well37.3 tok/s5194 ms33K
Agentic CodingSRuns well37.3 tok/s7555 ms33K
ReasoningSRuns well37.3 tok/s6139 ms33K
RAGSRuns well37.3 tok/s9444 ms33K

Quantization options

How Qwen 2.5 VL 72B (72B params) fits at each quantization level on RTX PRO 6000 Blackwell Workstation Edition 96GB (96.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
28.1 GB
LowA83
Q3_K_S
3
35.3 GB
LowA84
NVFP4
4
40.3 GB
MediumS86
Q4_K_M
4
43.9 GB
MediumS86
Q5_K_M
5
51.8 GB
HighS88
Q6_K
6
59.0 GB
HighS88
Q8_0Best for your GPU
8
77.0 GB
Very HighS88
F16
16
147.6 GB
MaximumF0

Get started

Copy-paste commands to run Qwen 2.5 VL 72B on your machine.

Run

lms load Qwen2.5-VL-72B-Instruct && lms server start

Your hardware

More models your RTX PRO 6000 Blackwell Workstation Edition 96GB can run

ModelParamsGradeDecodeCapabilities
MistralDevstral 2 123B Instruct123BS21.8 tok/s
AlibabaQwen 3.5 122B A10B122BS60.5 tok/s
MistralMistral Small 4 119B119BS65.6 tok/s
OpenAIGPT-OSS 120B117BS22.9 tok/s
CohereCommand A 111B111BS24.3 tok/s

Frequently asked questions

Can RTX PRO 6000 Blackwell Workstation Edition 96GB run Qwen 2.5 VL 72B?

Yes, RTX PRO 6000 Blackwell Workstation Edition 96GB can run Qwen 2.5 VL 72B with a S grade (Runs well). Expected decode speed: 37.3 tok/s.

How much VRAM does Qwen 2.5 VL 72B need?

Qwen 2.5 VL 72B (72B parameters) requires approximately 59.3 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 2.5 VL 72B?

The recommended quantization for Qwen 2.5 VL 72B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 2.5 VL 72B run at on RTX PRO 6000 Blackwell Workstation Edition 96GB?

On RTX PRO 6000 Blackwell Workstation Edition 96GB, Qwen 2.5 VL 72B achieves approximately 37.3 tokens per second decode speed with a time-to-first-token of 5194ms using Q4_K_M quantization.

Can RTX PRO 6000 Blackwell Workstation Edition 96GB run Qwen 2.5 VL 72B for coding?

For coding workloads, Qwen 2.5 VL 72B on RTX PRO 6000 Blackwell Workstation Edition 96GB receives a S grade with 37.3 tok/s and 33K context.

What context window can Qwen 2.5 VL 72B use on RTX PRO 6000 Blackwell Workstation Edition 96GB?

On RTX PRO 6000 Blackwell Workstation Edition 96GB, Qwen 2.5 VL 72B can safely use up to 33K tokens of context. The model's official context limit is 33K, but available memory constrains the safe maximum.

See all results for RTX PRO 6000 Blackwell Workstation Edition 96GBSee all hardware for Qwen 2.5 VL 72B
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