Can BaichuanMed OCR 72B i1 run on AMD Instinct MI250 128GB?

YES — Runs Great

C50Usable

Estimated from fit model

BaichuanMed OCR 72B i1 needs ~66.1 GB VRAM. AMD Instinct MI250 128GB has 128.0 GB. With Q4_K_M quantization, expect ~50 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 66.1 GB, 49.5 tok/s, Runs well

66.1 GB required128.0 GB available

52% VRAM used

Fit status

Runs well

Decode

49.5 tok/s

TTFT

3908 ms

Safe context

133K

Memory

66.1 GB / 128.0 GB

Memory breakdown

Weights43.9 GB

KV Cache8.4 GB

Runtime0.9 GB

Headroom12.8 GB

See how fast it feels

See how fast it feelsBaichuanMed OCR 72B i1 on AMD Instinct MI250 128GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 49.5 tok/s decode · 3.9s TTFT (warm) · 124 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	49.5 tok/s	2131 ms	133K
Coding	C	Runs well	49.5 tok/s	3908 ms	133K
Agentic Coding	C	Runs well	49.5 tok/s	5684 ms	133K
Reasoning	C	Runs well	49.5 tok/s	4618 ms	133K
RAG	C	Runs well	49.5 tok/s	7105 ms	133K

Quantization options

How BaichuanMed OCR 72B i1 (72B params) fits at each quantization level on AMD Instinct MI250 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	28.1 GB	Low	D40
Q3_K_S	3	35.3 GB	Low	C41
NVFP4	4	40.3 GB	Medium	C42
Q4_K_M	4	43.9 GB	Medium	C43
Q5_K_M	5	51.8 GB	High	C44
Q6_K	6	59.0 GB	High	C45
Q8_0Best for your GPU	8	77.0 GB	Very High	C47
F16	16	147.6 GB	Maximum	F0

Get started

Copy-paste commands to run BaichuanMed OCR 72B i1 on your machine.

Run

lms load hf-mradermacher--baichuanmed-ocr-72b-i1-gguf && lms server start

Upgrade-Optionen

Hardware, die BaichuanMed OCR 72B i1 gut ausführt

NVIDIA H200 141GBGünstige Wahl

141 GB VRAM (+13)4800 GB/s (+1600)

Raises estimated decode speed by about 85%.91.8 tok/s Dekodierung

Raises estimated decode speed by about 85%.

ca. $30,000 MSRP

NVIDIA H200 PCIe 141GBBestes Preis-Leistungs-Verhältnis

141 GB VRAM (+13)4800 GB/s (+1600)

Raises estimated decode speed by about 85%.91.8 tok/s Dekodierung

Raises estimated decode speed by about 85%.

ca. $30,000 MSRP

Frequently asked questions

Can AMD Instinct MI250 128GB run BaichuanMed OCR 72B i1?

Yes, AMD Instinct MI250 128GB can run BaichuanMed OCR 72B i1 with a C grade (Runs well). Expected decode speed: 49.5 tok/s.

How much VRAM does BaichuanMed OCR 72B i1 need?

BaichuanMed OCR 72B i1 (72B parameters) requires approximately 66.1 GB of memory with Q4_K_M quantization.

What is the best quantization for BaichuanMed OCR 72B i1?

The recommended quantization for BaichuanMed OCR 72B i1 is Q4_K_M, which balances quality and memory efficiency.

What speed will BaichuanMed OCR 72B i1 run at on AMD Instinct MI250 128GB?

On AMD Instinct MI250 128GB, BaichuanMed OCR 72B i1 achieves approximately 49.5 tokens per second decode speed with a time-to-first-token of 3908ms using Q4_K_M quantization.

Can AMD Instinct MI250 128GB run BaichuanMed OCR 72B i1 for coding?

For coding workloads, BaichuanMed OCR 72B i1 on AMD Instinct MI250 128GB receives a C grade with 49.5 tok/s and 133K context.

What context window can BaichuanMed OCR 72B i1 use on AMD Instinct MI250 128GB?

On AMD Instinct MI250 128GB, BaichuanMed OCR 72B i1 can safely use up to 133K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250 128GB See all hardware for BaichuanMed OCR 72B i1

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