Can Baichuan M2 32B Q4 K M run on AMD Instinct MI250X 128GB?

YES — Runs Great

C48Usable

Estimated from fit model

Baichuan M2 32B Q4 K M needs ~37.0 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~128 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 37.0 GB, 127.9 tok/s, Runs well

37.0 GB required128.0 GB available

29% VRAM used

Fit status

Runs well

Decode

127.9 tok/s

TTFT

1514 ms

Safe context

404K

Memory

37.0 GB / 128.0 GB

Memory breakdown

Weights19.5 GB

KV Cache3.8 GB

Runtime0.9 GB

Headroom12.8 GB

See how fast it feels

See how fast it feelsBaichuan M2 32B Q4 K M on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 127.9 tok/s decode · 1.5s TTFT (warm) · 320 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	127.9 tok/s	826 ms	404K
Coding	C	Runs well	127.9 tok/s	1514 ms	404K
Agentic Coding	C	Runs well	127.9 tok/s	2202 ms	404K
Reasoning	C	Runs well	127.9 tok/s	1789 ms	404K
RAG	C	Runs well	127.9 tok/s	2753 ms	404K

Quantization options

How Baichuan M2 32B Q4 K M (32B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	12.5 GB	Low	D38
Q3_K_S	3	15.7 GB	Low	D38
NVFP4	4	17.9 GB	Medium	D39
Q4_K_M	4	19.5 GB	Medium	D39
Q5_K_M	5	23.0 GB	High	D39
Q6_K	6	26.2 GB	High	D39
Q8_0	8	34.2 GB	Very High	C41
F16Best for your GPU	16	65.6 GB	Maximum	C46

Get started

Copy-paste commands to run Baichuan M2 32B Q4 K M on your machine.

Run

lms load hf-baichuan-inc--baichuan-m2-32b-q4-k-m-gguf && lms server start

Frequently asked questions

Can AMD Instinct MI250X 128GB run Baichuan M2 32B Q4 K M?

Yes, AMD Instinct MI250X 128GB can run Baichuan M2 32B Q4 K M with a C grade (Runs well). Expected decode speed: 127.9 tok/s.

How much VRAM does Baichuan M2 32B Q4 K M need?

Baichuan M2 32B Q4 K M (32B parameters) requires approximately 37.0 GB of memory with Q4_K_M quantization.

What is the best quantization for Baichuan M2 32B Q4 K M?

The recommended quantization for Baichuan M2 32B Q4 K M is Q4_K_M, which balances quality and memory efficiency.

What speed will Baichuan M2 32B Q4 K M run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Baichuan M2 32B Q4 K M achieves approximately 127.9 tokens per second decode speed with a time-to-first-token of 1514ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Baichuan M2 32B Q4 K M for coding?

For coding workloads, Baichuan M2 32B Q4 K M on AMD Instinct MI250X 128GB receives a C grade with 127.9 tok/s and 404K context.

What context window can Baichuan M2 32B Q4 K M use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Baichuan M2 32B Q4 K M can safely use up to 404K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GB See all hardware for Baichuan M2 32B Q4 K M

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