Can Gemma 3 27B run on AMD Instinct MI210 64GB?

YES — Runs Great

S85Excellent
Estimated from fit model

Gemma 3 27B needs ~35.3 GB VRAM. AMD Instinct MI210 64GB has 64.0 GB. With Q4_K_M quantization, expect ~71 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: HighStack: BasicBottleneck: Balanced
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Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) 35.3 GB, 71.0 tok/s, Runs well
35.3 GB required64.0 GB available
55% VRAM used

Fit status

Runs well

Decode

71.0 tok/s

TTFT

2726 ms

Safe context

57K

Memory

35.3 GB / 64.0 GB

Memory breakdown

Weights16.5 GB
KV Cache11.2 GB
Runtime1.2 GB
Headroom6.4 GB

See how fast it feels

See how fast it feelsGemma 3 27B on AMD Instinct MI210 64GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort: def quicksort(arr): if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) # Example usage numbers = [3, 6, 8, 10, 1, 2, 1] print(quicksort(numbers)) # [1, 1, 2, 3, 6, 8, 10] The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]: """Sort a list using the quicksort algorithm. Args: arr: List of integers to sort. Returns: A new sorted list. """ if len(arr) <= 1: return arr pivot = arr[len(arr) // 2] left = [x for x in arr if x < pivot] middle = [x for x in arr if x == pivot] right = [x for x in arr if x > pivot] return quicksort(left) + middle + quicksort(right) Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 71.0 tok/s decode · 2.7s TTFT (warm) · 178 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

WorkloadGradeFitDecodeTTFTContext
ChatARuns well71.0 tok/s1487 ms57K
CodingSRuns well71.0 tok/s2726 ms57K
Agentic CodingSRuns well71.0 tok/s3966 ms57K
ReasoningSRuns well71.0 tok/s3222 ms57K
RAGSRuns well71.0 tok/s4957 ms57K

Quantization options

How Gemma 3 27B (27B params) fits at each quantization level on AMD Instinct MI210 64GB (64.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
10.5 GB
LowA74
Q3_K_S
3
13.2 GB
LowA74
NVFP4
4
15.1 GB
MediumA75
Q4_K_M
4
16.5 GB
MediumA75
Q5_K_M
5
19.4 GB
HighA76
Q6_K
6
22.1 GB
HighA76
Q8_0Best for your GPU
8
28.9 GB
Very HighA78
F16
16
55.4 GB
MaximumF0

Get started

Copy-paste commands to run Gemma 3 27B on your machine.

Run

ollama run gemma3

Your hardware

More models your AMD Instinct MI210 64GB can run

ModelParamsGradeDecodeCapabilities
AlibabaQwen3-Coder 30B A3B Instruct30.5BS168.4 tok/s
AlibabaQwen 3.6 35B A3B35BS141.5 tok/s
AlibabaQwen3-VL 30B A3B Instruct30BS174.2 tok/s
AlibabaQwen 3.5 35B A3B35BS153.9 tok/s
AlibabaQwen 3 32B32BS62.1 tok/s

Frequently asked questions

Can AMD Instinct MI210 64GB run Gemma 3 27B?

Yes, AMD Instinct MI210 64GB can run Gemma 3 27B with a S grade (Runs well). Expected decode speed: 71.0 tok/s.

How much VRAM does Gemma 3 27B need?

Gemma 3 27B (27B parameters) requires approximately 35.3 GB of memory with Q4_K_M quantization.

What is the best quantization for Gemma 3 27B?

The recommended quantization for Gemma 3 27B is Q4_K_M, which balances quality and memory efficiency.

What speed will Gemma 3 27B run at on AMD Instinct MI210 64GB?

On AMD Instinct MI210 64GB, Gemma 3 27B achieves approximately 71.0 tokens per second decode speed with a time-to-first-token of 2726ms using Q4_K_M quantization.

Can AMD Instinct MI210 64GB run Gemma 3 27B for coding?

For coding workloads, Gemma 3 27B on AMD Instinct MI210 64GB receives a S grade with 71.0 tok/s and 57K context.

What context window can Gemma 3 27B use on AMD Instinct MI210 64GB?

On AMD Instinct MI210 64GB, Gemma 3 27B can safely use up to 57K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI210 64GBSee all hardware for Gemma 3 27B
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