Can Yi 34B Chat run on AMD Instinct MI325X 256GB?

YES — Runs Great

C48Usable

Estimated from fit model

Yi 34B Chat needs ~50.9 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~229 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 50.9 GB, 229.3 tok/s, Runs well

50.9 GB required256.0 GB available

20% VRAM used

Fit status

Runs well

Decode

229.3 tok/s

TTFT

844 ms

Safe context

200K

Memory

50.9 GB / 256.0 GB

Memory breakdown

Weights20.7 GB

KV Cache3.7 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsYi 34B Chat on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 229.3 tok/s decode · 844ms TTFT (warm) · 573 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	229.3 tok/s	461 ms	200K
Coding	C	Runs well	229.3 tok/s	844 ms	200K
Agentic Coding	C	Runs well	229.3 tok/s	1228 ms	200K
Reasoning	C	Runs well	229.3 tok/s	998 ms	200K
RAG	C	Runs well	229.3 tok/s	1535 ms	200K

Quantization options

How Yi 34B Chat (34B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	13.3 GB	Low	D38
Q3_K_S	3	16.7 GB	Low	D38
NVFP4	4	19.0 GB	Medium	D38
Q4_K_M	4	20.7 GB	Medium	D38
Q5_K_M	5	24.5 GB	High	D39
Q6_K	6	27.9 GB	High	D39
Q8_0	8	36.4 GB	Very High	D40
F16Best for your GPU	16	69.7 GB	Maximum	C43

Get started

Copy-paste commands to run Yi 34B Chat on your machine.

Run

lms load Yi-34B-Chat && lms server start

Frequently asked questions

Can AMD Instinct MI325X 256GB run Yi 34B Chat?

Yes, AMD Instinct MI325X 256GB can run Yi 34B Chat with a C grade (Runs well). Expected decode speed: 229.3 tok/s.

How much VRAM does Yi 34B Chat need?

Yi 34B Chat (34B parameters) requires approximately 50.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Yi 34B Chat?

The recommended quantization for Yi 34B Chat is Q4_K_M, which balances quality and memory efficiency.

What speed will Yi 34B Chat run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Yi 34B Chat achieves approximately 229.3 tokens per second decode speed with a time-to-first-token of 844ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Yi 34B Chat for coding?

For coding workloads, Yi 34B Chat on AMD Instinct MI325X 256GB receives a C grade with 229.3 tok/s and 200K context.

What context window can Yi 34B Chat use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Yi 34B Chat can safely use up to 200K tokens of context. The model's official context limit is 200K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for Yi 34B Chat

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<iframe src="https://willitrunai.com/embed/yi-34b-chat-on-instinct-mi325x-256gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>

Preview:

Workload

Grade

Fit

Decode

TTFT

Context

Chat

Runs well

229.3 tok/s

461 ms

200K

Coding

Runs well

229.3 tok/s

844 ms

200K

Agentic Coding

Runs well

229.3 tok/s

1228 ms

200K

Reasoning

Runs well

229.3 tok/s

998 ms

200K

RAG

Runs well

229.3 tok/s

1535 ms

200K

Quantization options

How Yi 34B Chat (34B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	13.3 GB	Low	D38
Q3_K_S	3	16.7 GB	Low	D38
NVFP4	4	19.0 GB	Medium	D38
Q4_K_M	4	20.7 GB	Medium	D38
Q5_K_M	5	24.5 GB	High	D39
Q6_K	6	27.9 GB	High	D39
Q8_0	8	36.4 GB	Very High	D40
F16Best for your GPU	16	69.7 GB	Maximum	C43

Frequently asked questions

Can AMD Instinct MI325X 256GB run Yi 34B Chat?

Yes, AMD Instinct MI325X 256GB can run Yi 34B Chat with a C grade (Runs well). Expected decode speed: 229.3 tok/s.

How much VRAM does Yi 34B Chat need?

Yi 34B Chat (34B parameters) requires approximately 50.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Yi 34B Chat?

The recommended quantization for Yi 34B Chat is Q4_K_M, which balances quality and memory efficiency.

What speed will Yi 34B Chat run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Yi 34B Chat achieves approximately 229.3 tokens per second decode speed with a time-to-first-token of 844ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Yi 34B Chat for coding?

For coding workloads, Yi 34B Chat on AMD Instinct MI325X 256GB receives a C grade with 229.3 tok/s and 200K context.

What context window can Yi 34B Chat use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Yi 34B Chat can safely use up to 200K tokens of context. The model's official context limit is 200K, but available memory constrains the safe maximum.