Can Qwen 3.5 35B A3B run on AMD Instinct MI100 32GB?

YES — Tight Fit

S95Excellent

Estimated from fit model

Qwen 3.5 35B A3B needs ~26.9 GB VRAM. AMD Instinct MI100 32GB has 32.0 GB. With Q4_K_M quantization, expect ~110 tok/s.

Runtime: llama.cppCapacity: TightBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 26.9 GB, 110.3 tok/s, Tight fit

26.9 GB required32.0 GB available

84% VRAM used

Fit status

Tight fit

Decode

110.3 tok/s

TTFT

1755 ms

Safe context

72K

Memory

26.9 GB / 32.0 GB

Memory breakdown

Weights21.3 GB

KV Cache1.5 GB

Runtime0.9 GB

Headroom3.2 GB

See how fast it feels

See how fast it feelsQwen 3.5 35B A3B on AMD Instinct MI100 32GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 110.3 tok/s decode · 1.8s TTFT (warm) · 276 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	S	Runs well	110.3 tok/s	957 ms	72K
Coding	S	Tight fit	110.3 tok/s	1755 ms	72K
Agentic Coding	S	Tight fit	110.3 tok/s	2553 ms	72K
Reasoning	S	Tight fit	110.3 tok/s	2074 ms	72K
RAG	S	Tight fit	110.3 tok/s	3191 ms	72K

Inference speed

Qwen 3.5 35B A3B inference speed — tokens per second by GPU & Mac

Estimated decode speed (tokens/sec) for Qwen 3.5 35B A3B at Q4_K_M across popular GPUs and Apple Silicon, using the fastest local runtime per device. Fastest is RTX 5090 32GB at ~139 tok/s. Speed is memory-bandwidth bound, so cards that fit the whole model in VRAM run far faster than ones that offload to system RAM.

GPU / Mac	Memory	Quant	Speed (tok/s)	Fits?
RTX 5090 32GB	32 GB	Q4_K_M	139.4	Tight
Mac Studio M3 Ultra 256GB	256 GB	Q4_K_M	100.1	Fits
Mac Studio M2 Ultra 128GB	128 GB	Q4_K_M	83.4	Fits
Mac Studio M1 Ultra 128GB	128 GB	Q4_K_M	79.1	Fits
RTX 4090 24GB	24 GB	Q4_K_M	71.1	Heavy offload
MacBook Pro M4 Max 128GB	128 GB	Q4_K_M	61.8	Fits
MacBook Pro M4 Max 64GB	64 GB	Q4_K_M	61.8	Fits
RX 7900 XTX 24GB	24 GB	Q4_K_M	60.0	Heavy offload
RTX 3090 24GB	24 GB	Q4_K_M	56.9	Heavy offload
MacBook Pro M3 Max 64GB	64 GB	Q4_K_M	47.4	Fits
MacBook Pro M1 Max 64GB	64 GB	Q4_K_M	43.5	Fits
MacBook Pro M4 Pro 48GB	48 GB	Q4_K_M	41.5	Tight
RTX 4080 Super 16GB	16 GB	Q4_K_M	25.2	Too big
RTX 4070 12GB	12 GB	Q4_K_M	8.8	Too big
RTX 3060 12GB	12 GB	Q4_K_M	5.2	Too big
RTX 4060 8GB	8 GB	Q4_K_M	4.4	Too big

Estimates for single-stream decoding at Q4_K_M; real tokens/sec varies with prompt length, context, batch size, and runtime build. Prompt processing (prefill) is faster than the decode figures shown here.

Quantization options

How Qwen 3.5 35B A3B (35B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	13.7 GB	Low	S90
Q3_K_S	3	17.2 GB	Low	S91
NVFP4	4	19.6 GB	Medium	S91
Q4_K_M	4	21.3 GB	Medium	S90
Q5_K_MBest for your GPU	5	25.2 GB	High	S90
Q6_K	6	28.7 GB	High	F0
Q8_0	8	37.5 GB	Very High	F0
F16	16	71.8 GB	Maximum	F0

Get started

Copy-paste commands to run Qwen 3.5 35B A3B on your machine.

Run

ollama run qwen3.5:35b-a3b

Frequently asked questions

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B?

Yes, AMD Instinct MI100 32GB can run Qwen 3.5 35B A3B with a S grade (Tight fit). Expected decode speed: 110.3 tok/s.

How much VRAM does Qwen 3.5 35B A3B need?

Qwen 3.5 35B A3B (35B parameters) requires approximately 26.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 3.5 35B A3B?

The recommended quantization for Qwen 3.5 35B A3B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 3.5 35B A3B run at on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B achieves approximately 110.3 tokens per second decode speed with a time-to-first-token of 1755ms using Q4_K_M quantization.

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B for coding?

For coding workloads, Qwen 3.5 35B A3B on AMD Instinct MI100 32GB receives a S grade with 110.3 tok/s and 72K context.

What context window can Qwen 3.5 35B A3B use on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B can safely use up to 72K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI100 32GB See all hardware for Qwen 3.5 35B A3B

Embed this result▼

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<iframe src="https://willitrunai.com/embed/qwen-3.5-35b-a3b-on-instinct-mi100-32gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>

Preview:

Workload

Grade

Fit

Decode

TTFT

Context

Chat

Runs well

110.3 tok/s

957 ms

72K

Coding

Tight fit

110.3 tok/s

1755 ms

72K

Agentic Coding

Tight fit

110.3 tok/s

2553 ms

72K

Reasoning

Tight fit

110.3 tok/s

2074 ms

72K

RAG

Tight fit

110.3 tok/s

3191 ms

72K

Qwen 3.5 35B A3B inference speed — tokens per second by GPU & Mac

GPU / Mac

Memory

Quant

Speed (tok/s)

Fits?

RTX 5090 32GB

32 GB

Q4_K_M

139.4

Tight

Mac Studio M3 Ultra 256GB

256 GB

Q4_K_M

100.1

Fits

Mac Studio M2 Ultra 128GB

128 GB

Q4_K_M

83.4

Fits

Mac Studio M1 Ultra 128GB

128 GB

Q4_K_M

79.1

Fits

RTX 4090 24GB

24 GB

Q4_K_M

71.1

Heavy offload

MacBook Pro M4 Max 128GB

128 GB

Q4_K_M

61.8

Fits

MacBook Pro M4 Max 64GB

64 GB

Q4_K_M

61.8

Fits

RX 7900 XTX 24GB

24 GB

Q4_K_M

60.0

Heavy offload

RTX 3090 24GB

24 GB

Q4_K_M

56.9

Heavy offload

MacBook Pro M3 Max 64GB

64 GB

Q4_K_M

47.4

Fits

MacBook Pro M1 Max 64GB

64 GB

Q4_K_M

43.5

Fits

MacBook Pro M4 Pro 48GB

48 GB

Q4_K_M

41.5

Tight

RTX 4080 Super 16GB

16 GB

Q4_K_M

25.2

Too big

RTX 4070 12GB

12 GB

Q4_K_M

8.8

Too big

RTX 3060 12GB

12 GB

Q4_K_M

5.2

Too big

RTX 4060 8GB

8 GB

Q4_K_M

4.4

Too big

Quantization options

How Qwen 3.5 35B A3B (35B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	13.7 GB	Low	S90
Q3_K_S	3	17.2 GB	Low	S91
NVFP4	4	19.6 GB	Medium	S91
Q4_K_M	4	21.3 GB	Medium	S90
Q5_K_MBest for your GPU	5	25.2 GB	High	S90
Q6_K	6	28.7 GB	High	F0
Q8_0	8	37.5 GB	Very High	F0
F16	16	71.8 GB	Maximum	F0

Frequently asked questions

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B?

Yes, AMD Instinct MI100 32GB can run Qwen 3.5 35B A3B with a S grade (Tight fit). Expected decode speed: 110.3 tok/s.

How much VRAM does Qwen 3.5 35B A3B need?

Qwen 3.5 35B A3B (35B parameters) requires approximately 26.9 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen 3.5 35B A3B?

The recommended quantization for Qwen 3.5 35B A3B is Q4_K_M, which balances quality and memory efficiency.

What speed will Qwen 3.5 35B A3B run at on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B achieves approximately 110.3 tokens per second decode speed with a time-to-first-token of 1755ms using Q4_K_M quantization.

Can AMD Instinct MI100 32GB run Qwen 3.5 35B A3B for coding?

For coding workloads, Qwen 3.5 35B A3B on AMD Instinct MI100 32GB receives a S grade with 110.3 tok/s and 72K context.

What context window can Qwen 3.5 35B A3B use on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Qwen 3.5 35B A3B can safely use up to 72K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.