Qwen 2.5 72B needs ~52.4 GB but RTX PRO 4000 Blackwell 24GB only has 24.0 GB. Try a smaller quantization or lighter model.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
28.4 GB over capacity — needs offload or smaller quantization
Fit status
Too heavy
Decode
2.2 tok/s
TTFT
89094 ms
Safe context
4K
Memory
52.4 GB / 24.0 GB
Offload
50%
Usable VRAM is the main blocker for this model.
Not enough usable memory
The model needs 52.4 GB, but this setup only exposes 24.0 GB of usable VRAM.
Add more VRAM headroom
The first useful upgrade is more dedicated VRAM so you can fit the model without shrinking context or dropping to a much lower quant.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | F | Too heavy | 2.4 tok/s | 44090 ms | 4K |
| Coding | F | Too heavy | 2.2 tok/s | 89094 ms | 4K |
| Agentic Coding | F | Too heavy | 2.1 tok/s | 134315 ms | 4K |
| Reasoning | F | Too heavy | 2.2 tok/s | 105293 ms | 4K |
| RAG | F | Too heavy | 2.1 tok/s | 167894 ms | 4K |
How Qwen 2.5 72B (72B params) fits at each quantization level on RTX PRO 4000 Blackwell 24GB (24.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 28.1 GB | Low | F0 |
Q3_K_S | 3 | 35.3 GB | Low | F0 |
NVFP4 | 4 |
Upgrade options
RTX A6000 48GBBest valueMakes the model fit on the accelerator instead of staying completely out of reach.
Raises estimated decode speed by about 273%.
~$4,650 MSRP
RTX PRO 5000 Blackwell 48GBNVIDIA upgradeMakes the model fit on the accelerator instead of staying completely out of reach.
Raises estimated decode speed by about 641%.
~$4,999 MSRP
NVIDIA A16 64GBBudget pickMakes the model fit on the accelerator instead of staying completely out of reach.
Removes host-memory offload, which is usually the single biggest latency and throughput win.
~$6,500 MSRP
NVIDIA H100 80GBBiggest leapMakes the model fit on the accelerator instead of staying completely out of reach.
Removes host-memory offload, which is usually the single biggest latency and throughput win.
~$40,000 MSRP
No, Qwen 2.5 72B requires more memory than RTX PRO 4000 Blackwell 24GB provides.
Qwen 2.5 72B (72B parameters) requires approximately 52.4 GB of memory with Q4_K_M quantization.
The recommended quantization for Qwen 2.5 72B is Q4_K_M, which balances quality and memory efficiency.
On RTX PRO 4000 Blackwell 24GB, Qwen 2.5 72B achieves approximately 2.2 tokens per second decode speed with a time-to-first-token of 89094ms using Q4_K_M quantization.
For coding workloads, Qwen 2.5 72B on RTX PRO 4000 Blackwell 24GB receives a F grade with 2.2 tok/s and 4K context.
On RTX PRO 4000 Blackwell 24GB, Qwen 2.5 72B can safely use up to 4K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/qwen-2.5-72b-on-rtx-pro-4000-blackwell-24gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
Preview:
| Medium |
| F0 |
Q4_K_M | 4 | 43.9 GB | Medium | F0 |
Q5_K_M | 5 | 51.8 GB | High | F0 |
Q6_K | 6 | 59.0 GB | High | F0 |
Q8_0 | 8 | 77.0 GB | Very High | F0 |
F16 | 16 | 147.6 GB | Maximum | F0 |
Add more VRAM headroom. The first useful upgrade is more dedicated VRAM so you can fit the model without shrinking context or dropping to a much lower quant.
