Pixtral Large 124B needs ~94.7 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~36 tok/s.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
35.9 tok/s
TTFT
5395 ms
Safe context
115K
Memory
94.7 GB / 128.0 GB
This setup is broadly balanced for this model.
No major red flags
This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | S | Runs well | 35.9 tok/s | 2943 ms | 115K |
| Coding | S | Runs well | 35.9 tok/s | 5395 ms | 115K |
| Agentic Coding | S | Runs well | 35.9 tok/s | 7847 ms | 115K |
| Reasoning | S | Runs well | 35.9 tok/s | 6376 ms | 115K |
| RAG | S | Runs well | 35.9 tok/s | 9809 ms | 115K |
How Pixtral Large 124B (124B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 48.4 GB | Low | A84 |
Q3_K_S | 3 | 60.8 GB | Low | S86 |
NVFP4 | 4 | 69.4 GB | Medium | S87 |
Q4_K_M | 4 | 75.6 GB | Medium | S87 |
Q5_K_M | 5 | 89.3 GB | High | S87 |
Q6_KBest for your GPU | 6 | 101.7 GB | High | S87 |
Q8_0 | 8 | 132.7 GB | Very High | F0 |
F16 | 16 | 254.2 GB | Maximum | F0 |
Copy-paste commands to run Pixtral Large 124B on your machine.
Run
lms load Pixtral-Large-Instruct-2411 && lms server startYes, AMD Instinct MI250X 128GB can run Pixtral Large 124B with a S grade (Runs well). Expected decode speed: 35.9 tok/s.
Pixtral Large 124B (124B parameters) requires approximately 94.7 GB of memory with Q4_K_M quantization.
The recommended quantization for Pixtral Large 124B is Q4_K_M, which balances quality and memory efficiency.
On AMD Instinct MI250X 128GB, Pixtral Large 124B achieves approximately 35.9 tokens per second decode speed with a time-to-first-token of 5395ms using Q4_K_M quantization.
For coding workloads, Pixtral Large 124B on AMD Instinct MI250X 128GB receives a S grade with 35.9 tok/s and 115K context.
On AMD Instinct MI250X 128GB, Pixtral Large 124B can safely use up to 115K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/pixtral-large-124b-on-instinct-mi250x-128gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
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