Mixtral 8x7B needs ~57.1 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~315 tok/s.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
315.1 tok/s
TTFT
614 ms
Safe context
33K
Memory
57.1 GB / 256.0 GB
This setup is broadly balanced for this model.
No major red flags
This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | B | Runs well | 315.1 tok/s | 350 ms | 33K |
| Coding | B | Runs well | 315.1 tok/s | 614 ms | 33K |
| Agentic Coding | B | Runs well | 315.1 tok/s | 894 ms | 33K |
| Reasoning | B | Runs well | 315.1 tok/s | 726 ms | 33K |
| RAG | B | Runs well | 315.1 tok/s | 1117 ms | 33K |
How Mixtral 8x7B (47B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 18.3 GB | Low | C52 |
Q3_K_S | 3 | 23.0 GB | Low | C53 |
NVFP4 | 4 | 26.3 GB | Medium | C53 |
Q4_K_M | 4 | 28.7 GB | Medium | C53 |
Q5_K_M | 5 | 33.8 GB | High | C54 |
Q6_K | 6 | 38.5 GB | High | C54 |
Q8_0 | 8 | 50.3 GB | Very High | C55 |
F16Best for your GPU | 16 | 96.4 GB | Maximum | B59 |
Copy-paste commands to run Mixtral 8x7B on your machine.
Run
ollama run mixtralYes, AMD Instinct MI325X 256GB can run Mixtral 8x7B with a B grade (Runs well). Expected decode speed: 315.1 tok/s.
Mixtral 8x7B (47B parameters) requires approximately 57.1 GB of memory with Q4_K_M quantization.
The recommended quantization for Mixtral 8x7B is Q4_K_M, which balances quality and memory efficiency.
On AMD Instinct MI325X 256GB, Mixtral 8x7B achieves approximately 315.1 tokens per second decode speed with a time-to-first-token of 614ms using Q4_K_M quantization.
For coding workloads, Mixtral 8x7B on AMD Instinct MI325X 256GB receives a B grade with 315.1 tok/s and 33K context.
On AMD Instinct MI325X 256GB, Mixtral 8x7B can safely use up to 33K tokens of context. The model's official context limit is 33K, but available memory constrains the safe maximum.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/mixtral-8x7b-on-instinct-mi325x-256gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
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