Mixtral 8x7B needs ~44.3 GB VRAM. AMD Instinct MI300A 128GB has 128.0 GB. With Q4_K_M quantization, expect ~267 tok/s.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
266.9 tok/s
TTFT
725 ms
Safe context
33K
Memory
44.3 GB / 128.0 GB
This setup is broadly balanced for this model.
No major red flags
This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | B | Runs well | 266.9 tok/s | 396 ms | 33K |
| Coding | B | Runs well | 266.9 tok/s | 725 ms | 33K |
| Agentic Coding | B | Runs well | 266.9 tok/s | 1055 ms | 33K |
| Reasoning | B | Runs well | 266.9 tok/s | 857 ms | 33K |
| RAG | B | Runs well | 266.9 tok/s | 1319 ms | 33K |
How Mixtral 8x7B (47B params) fits at each quantization level on AMD Instinct MI300A 128GB (128.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 18.3 GB | Low | C54 |
Q3_K_S | 3 | 23.0 GB | Low | C55 |
NVFP4 | 4 | 26.3 GB | Medium | B55 |
Q4_K_M | 4 | 28.7 GB | Medium | B56 |
Q5_K_M | 5 | 33.8 GB | High | B57 |
Q6_K | 6 | 38.5 GB | High | B57 |
Q8_0 | 8 | 50.3 GB | Very High | B59 |
F16Best for your GPU | 16 | 96.4 GB | Maximum | B63 |
Copy-paste commands to run Mixtral 8x7B on your machine.
Run
ollama run mixtralYes, AMD Instinct MI300A 128GB can run Mixtral 8x7B with a B grade (Runs well). Expected decode speed: 266.9 tok/s.
Mixtral 8x7B (47B parameters) requires approximately 44.3 GB of memory with Q4_K_M quantization.
The recommended quantization for Mixtral 8x7B is Q4_K_M, which balances quality and memory efficiency.
On AMD Instinct MI300A 128GB, Mixtral 8x7B achieves approximately 266.9 tokens per second decode speed with a time-to-first-token of 725ms using Q4_K_M quantization.
For coding workloads, Mixtral 8x7B on AMD Instinct MI300A 128GB receives a B grade with 266.9 tok/s and 33K context.
On AMD Instinct MI300A 128GB, Mixtral 8x7B can safely use up to 33K tokens of context. The model's official context limit is 33K, but available memory constrains the safe maximum.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/mixtral-8x7b-on-instinct-mi300a-128gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
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