Qwen3.5 397B A17B needs ~221.8 GB VRAM. B100 192GB has 192.0 GB. With Q2_K quantization, expect ~25 tok/s.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
117.1 GB over capacity — needs offload or smaller quantization
Fit status
Too heavy
Decode
10.8 tok/s
TTFT
17945 ms
Safe context
4K
Memory
309.1 GB / 192.0 GB
Offload
40%
It fits through host-memory offload, and offload is the main reason performance drops.
CPU or host-memory offload is active
About 10% of the working set spills out of accelerator memory, which usually hurts latency and sustained decode throughput.
Very little memory headroom
You can run the model, but there is not much room left for longer context, bigger batches, extra apps, or future model updates.
Remove offload with more accelerator memory
Prioritize a GPU or unified-memory tier that fits the whole model natively. Removing offload usually helps more than small compute gains.
Buy headroom, not only minimum fit
A slightly larger memory tier gives you safer context growth and makes the recommendation more future-proof.
Increase host RAM if you keep offloading
This setup may need roughly 20.8 GB of extra host RAM just for the offloaded portion, before OS and other tools.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | F | Too heavy | 12.3 tok/s | 8603 ms | 4K |
| Coding | F | Too heavy | 10.8 tok/s | 17945 ms | 4K |
| Agentic Coding | F | Too heavy | 8.6 tok/s | 32896 ms | 4K |
| Reasoning | F | Too heavy | 10.8 tok/s | 21207 ms | 4K |
| RAG | F | Too heavy | 8.6 tok/s | 41120 ms | 4K |
How Qwen3.5 397B A17B (397B params) fits at each quantization level on B100 192GB (192.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 154.8 GB | Low | F0 |
Q3_K_S | 3 | 194.5 GB | Low | F0 |
NVFP4 | 4 |
Copy-paste commands to run Qwen3.5 397B A17B on your machine.
Run
lms load hf-unsloth--qwen3-5-397b-a17b-gguf && lms server startUpgrade options
Yes, B100 192GB can run Qwen3.5 397B A17B at Q2_K quantization (Very compromised (needs ~20.8 GB host RAM)). The recommended Q4_K_M requires 309.1 GB which exceeds available memory, but at Q2_K it needs only 221.8 GB. Expected decode speed: 24.8 tok/s.
Qwen3.5 397B A17B (397B parameters) requires approximately 309.1 GB at Q4_K_M quantization. On B100 192GB, it fits at Q2_K using 221.8 GB.
The recommended quantization is Q4_K_M, but on B100 192GB the best fitting quantization is Q2_K, which uses 221.8 GB.
On B100 192GB, Qwen3.5 397B A17B achieves approximately 24.8 tokens per second decode speed with a time-to-first-token of 7804ms using Q2_K quantization.
For coding workloads, Qwen3.5 397B A17B on B100 192GB receives a F grade with 10.8 tok/s and 4K context.
On B100 192GB, Qwen3.5 397B A17B can safely use up to 6K tokens of context at Q2_K quantization. The model's official context limit is —, but available memory constrains the safe maximum.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/hf-unsloth--qwen3-5-397b-a17b-gguf-on-b100-192gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
Preview:
| Medium |
| F0 |
Q4_K_M | 4 | 242.2 GB | Medium | F0 |
Q5_K_M | 5 | 285.8 GB | High | F0 |
Q6_K | 6 | 325.5 GB | High | F0 |
Q8_0 | 8 | 424.8 GB | Very High | F0 |
F16 | 16 | 813.8 GB | Maximum | F0 |
Remove offload with more accelerator memory. Prioritize a GPU or unified-memory tier that fits the whole model natively. Removing offload usually helps more than small compute gains.