Can Mistral 7B Instruct v0.3 run on RX 6600 8GB?

YES — Tight Fit

C50Usable

Estimated from fit model

Mistral 7B Instruct v0.3 needs ~6.8 GB VRAM. RX 6600 8GB has 8.0 GB. With Q4_K_M quantization, expect ~26 tok/s.

Runtime: llama.cppCapacity: TightBandwidth: Very lowStack: StandardBottleneck: Memory bandwidth

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 6.8 GB, 25.7 tok/s, Tight fit

6.8 GB required8.0 GB available

85% VRAM used

Fit status

Tight fit

Decode

25.7 tok/s

TTFT

7532 ms

Safe context

40K

Memory

6.8 GB / 8.0 GB

Memory breakdown

Weights4.3 GB

KV Cache0.8 GB

Runtime0.9 GB

Headroom0.8 GB

See how fast it feels

See how fast it feelsMistral 7B Instruct v0.3 on RX 6600 8GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 25.7 tok/s decode · 7.5s TTFT (warm) · 64 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	25.7 tok/s	4108 ms	40K
Coding	C	Tight fit	25.7 tok/s	7532 ms	40K
Agentic Coding	C	Runs with offload	25.7 tok/s	10955 ms	40K
Reasoning	C	Tight fit	25.7 tok/s	8901 ms	40K
RAG	C	Runs with offload	25.7 tok/s	13694 ms	40K

Quantization options

How Mistral 7B Instruct v0.3 (7B params) fits at each quantization level on RX 6600 8GB (8.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	2.7 GB	Low	C53
Q3_K_S	3	3.4 GB	Low	C54
NVFP4	4

Get started

Copy-paste commands to run Mistral 7B Instruct v0.3 on your machine.

Run

lms load hf-sanctumai--mistral-7b-instruct-v0-3-gguf && lms server start

Upgrade options

Hardware that runs Mistral 7B Instruct v0.3 well

RX 9060 XT 16GBBudget pick

16 GB VRAM (+8)320 GB/s (+96)

Raises estimated decode speed by about 84%.47.2 tok/s decode

Raises estimated decode speed by about 84%.

Adds memory headroom for longer context windows and future model growth.

~$349 MSRP

RX 7700 XT 12GBBest value

12 GB VRAM (+4)432 GB/s (+208)

Raises estimated decode speed by about 136%.60.7 tok/s decode

Raises estimated decode speed by about 136%.

Adds memory headroom for longer context windows and future model growth.

~$449 MSRP

RX 6700 XT 12GBAMD upgrade

12 GB VRAM (+4)384 GB/s (+160)

Raises estimated decode speed by about 82%.46.8 tok/s decode

Raises estimated decode speed by about 82%.

Adds memory headroom for longer context windows and future model growth.

~$479 MSRP

Frequently asked questions

Can RX 6600 8GB run Mistral 7B Instruct v0.3?

Yes, RX 6600 8GB can run Mistral 7B Instruct v0.3 with a C grade (Tight fit). Expected decode speed: 25.7 tok/s.

How much VRAM does Mistral 7B Instruct v0.3 need?

Mistral 7B Instruct v0.3 (7B parameters) requires approximately 6.8 GB of memory with Q4_K_M quantization.

What is the best quantization for Mistral 7B Instruct v0.3?

The recommended quantization for Mistral 7B Instruct v0.3 is Q4_K_M, which balances quality and memory efficiency.

What speed will Mistral 7B Instruct v0.3 run at on RX 6600 8GB?

On RX 6600 8GB, Mistral 7B Instruct v0.3 achieves approximately 25.7 tokens per second decode speed with a time-to-first-token of 7532ms using Q4_K_M quantization.

Can RX 6600 8GB run Mistral 7B Instruct v0.3 for coding?

For coding workloads, Mistral 7B Instruct v0.3 on RX 6600 8GB receives a C grade with 25.7 tok/s and 40K context.

What context window can Mistral 7B Instruct v0.3 use on RX 6600 8GB?

On RX 6600 8GB, Mistral 7B Instruct v0.3 can safely use up to 40K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for RX 6600 8GB See all hardware for Mistral 7B Instruct v0.3

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