Can Codestral 21B Pruned i1 run on AMD Instinct MI250X 128GB?

YES — Runs Great

C46Usable

Estimated from fit model

Codestral 21B Pruned i1 needs ~29.0 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~195 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 29.0 GB, 194.8 tok/s, Runs well

29.0 GB required128.0 GB available

23% VRAM used

Fit status

Runs well

Decode

194.8 tok/s

TTFT

994 ms

Safe context

660K

Memory

29.0 GB / 128.0 GB

Memory breakdown

Weights12.8 GB

KV Cache2.5 GB

Runtime0.9 GB

Headroom12.8 GB

See how fast it feels

See how fast it feelsCodestral 21B Pruned i1 on AMD Instinct MI250X 128GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 194.8 tok/s decode · 994ms TTFT (warm) · 487 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	194.8 tok/s	542 ms	660K
Coding	C	Runs well	194.8 tok/s	994 ms	660K
Agentic Coding	C	Runs well	194.8 tok/s	1445 ms	660K
Reasoning	C	Runs well	194.8 tok/s	1174 ms	660K
RAG	C	Runs well	194.8 tok/s	1807 ms	660K

Quantization options

How Codestral 21B Pruned i1 (21B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	8.2 GB	Low	D38
Q3_K_S	3	10.3 GB	Low	D38
NVFP4	4	11.8 GB	Medium	D38
Q4_K_M	4	12.8 GB	Medium	D38
Q5_K_M	5	15.1 GB	High	D38
Q6_K	6	17.2 GB	High	D38
Q8_0	8	22.5 GB	Very High	D39
F16Best for your GPU	16	43.1 GB	Maximum	C42

Get started

Copy-paste commands to run Codestral 21B Pruned i1 on your machine.

Run

lms load hf-mradermacher--codestral-21b-pruned-i1-gguf && lms server start

Frequently asked questions

Can AMD Instinct MI250X 128GB run Codestral 21B Pruned i1?

Yes, AMD Instinct MI250X 128GB can run Codestral 21B Pruned i1 with a C grade (Runs well). Expected decode speed: 194.8 tok/s.

How much VRAM does Codestral 21B Pruned i1 need?

Codestral 21B Pruned i1 (21B parameters) requires approximately 29.0 GB of memory with Q4_K_M quantization.

What is the best quantization for Codestral 21B Pruned i1?

The recommended quantization for Codestral 21B Pruned i1 is Q4_K_M, which balances quality and memory efficiency.

What speed will Codestral 21B Pruned i1 run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Codestral 21B Pruned i1 achieves approximately 194.8 tokens per second decode speed with a time-to-first-token of 994ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Codestral 21B Pruned i1 for coding?

For coding workloads, Codestral 21B Pruned i1 on AMD Instinct MI250X 128GB receives a C grade with 194.8 tok/s and 660K context.

What context window can Codestral 21B Pruned i1 use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Codestral 21B Pruned i1 can safely use up to 660K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI250X 128GB See all hardware for Codestral 21B Pruned i1

Embed this result▼

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<iframe src="https://willitrunai.com/embed/hf-mradermacher--codestral-21b-pruned-i1-gguf-on-instinct-mi250x-128gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>

Preview:

Workload

Grade

Fit

Decode

TTFT

Context

Chat

Runs well

194.8 tok/s

542 ms

660K

Coding

Runs well

194.8 tok/s

994 ms

660K

Agentic Coding

Runs well

194.8 tok/s

1445 ms

660K

Reasoning

Runs well

194.8 tok/s

1174 ms

660K

RAG

Runs well

194.8 tok/s

1807 ms

660K

Quantization options

How Codestral 21B Pruned i1 (21B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	8.2 GB	Low	D38
Q3_K_S	3	10.3 GB	Low	D38
NVFP4	4	11.8 GB	Medium	D38
Q4_K_M	4	12.8 GB	Medium	D38
Q5_K_M	5	15.1 GB	High	D38
Q6_K	6	17.2 GB	High	D38
Q8_0	8	22.5 GB	Very High	D39
F16Best for your GPU	16	43.1 GB	Maximum	C42

Frequently asked questions

Can AMD Instinct MI250X 128GB run Codestral 21B Pruned i1?

Yes, AMD Instinct MI250X 128GB can run Codestral 21B Pruned i1 with a C grade (Runs well). Expected decode speed: 194.8 tok/s.

How much VRAM does Codestral 21B Pruned i1 need?

Codestral 21B Pruned i1 (21B parameters) requires approximately 29.0 GB of memory with Q4_K_M quantization.

What is the best quantization for Codestral 21B Pruned i1?

The recommended quantization for Codestral 21B Pruned i1 is Q4_K_M, which balances quality and memory efficiency.

What speed will Codestral 21B Pruned i1 run at on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Codestral 21B Pruned i1 achieves approximately 194.8 tokens per second decode speed with a time-to-first-token of 994ms using Q4_K_M quantization.

Can AMD Instinct MI250X 128GB run Codestral 21B Pruned i1 for coding?

For coding workloads, Codestral 21B Pruned i1 on AMD Instinct MI250X 128GB receives a C grade with 194.8 tok/s and 660K context.

What context window can Codestral 21B Pruned i1 use on AMD Instinct MI250X 128GB?

On AMD Instinct MI250X 128GB, Codestral 21B Pruned i1 can safely use up to 660K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.