Can Mistral Small 24B Instruct 2501 run on NVIDIA H100 80GB?

YES — Runs Great

C49Usable

Estimated from fit model

Mistral Small 24B Instruct 2501 needs ~26.7 GB VRAM. NVIDIA H100 80GB has 80.0 GB. With Q4_K_M quantization, expect ~192 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: HighStack: BasicBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 26.7 GB, 192.2 tok/s, Runs well

26.7 GB required80.0 GB available

33% VRAM used

Fit status

Runs well

Decode

192.2 tok/s

TTFT

1007 ms

Safe context

319K

Memory

26.7 GB / 80.0 GB

Memory breakdown

Weights14.6 GB

KV Cache2.8 GB

Runtime1.2 GB

Headroom8.0 GB

See how fast it feels

See how fast it feelsMistral Small 24B Instruct 2501 on NVIDIA H100 80GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 192.2 tok/s decode · 1.0s TTFT (warm) · 481 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	192.2 tok/s	549 ms	319K
Coding	C	Runs well	192.2 tok/s	1007 ms	319K
Agentic Coding	C	Runs well	192.2 tok/s	1465 ms	319K
Reasoning	C	Runs well	192.2 tok/s	1190 ms	319K
RAG	C	Runs well	192.2 tok/s	1831 ms	319K

Quantization options

How Mistral Small 24B Instruct 2501 (24B params) fits at each quantization level on NVIDIA H100 80GB (80.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	9.4 GB	Low	C40
Q3_K_S	3	11.8 GB	Low	C41
NVFP4	4	13.4 GB	Medium	C41
Q4_K_M	4	14.6 GB	Medium	C41
Q5_K_M	5	17.3 GB	High	C41
Q6_K	6	19.7 GB	High	C42
Q8_0	8	25.7 GB	Very High	C43
F16Best for your GPU	16	49.2 GB	Maximum	C48

Get started

Copy-paste commands to run Mistral Small 24B Instruct 2501 on your machine.

Run

lms load hf-maziyarpanahi--mistral-small-24b-instruct-2501-gguf && lms server start

Frequently asked questions

Can NVIDIA H100 80GB run Mistral Small 24B Instruct 2501?

Yes, NVIDIA H100 80GB can run Mistral Small 24B Instruct 2501 with a C grade (Runs well). Expected decode speed: 192.2 tok/s.

How much VRAM does Mistral Small 24B Instruct 2501 need?

Mistral Small 24B Instruct 2501 (24B parameters) requires approximately 26.7 GB of memory with Q4_K_M quantization.

What is the best quantization for Mistral Small 24B Instruct 2501?

The recommended quantization for Mistral Small 24B Instruct 2501 is Q4_K_M, which balances quality and memory efficiency.

What speed will Mistral Small 24B Instruct 2501 run at on NVIDIA H100 80GB?

On NVIDIA H100 80GB, Mistral Small 24B Instruct 2501 achieves approximately 192.2 tokens per second decode speed with a time-to-first-token of 1007ms using Q4_K_M quantization.

Can NVIDIA H100 80GB run Mistral Small 24B Instruct 2501 for coding?

For coding workloads, Mistral Small 24B Instruct 2501 on NVIDIA H100 80GB receives a C grade with 192.2 tok/s and 319K context.

What context window can Mistral Small 24B Instruct 2501 use on NVIDIA H100 80GB?

On NVIDIA H100 80GB, Mistral Small 24B Instruct 2501 can safely use up to 319K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for NVIDIA H100 80GB See all hardware for Mistral Small 24B Instruct 2501

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Preview:

Workload

Grade

Fit

Decode

TTFT

Context

Chat

Runs well

192.2 tok/s

549 ms

319K

Coding

Runs well

192.2 tok/s

1007 ms

319K

Agentic Coding

Runs well

192.2 tok/s

1465 ms

319K

Reasoning

Runs well

192.2 tok/s

1190 ms

319K

RAG

Runs well

192.2 tok/s

1831 ms

319K

Quantization options

How Mistral Small 24B Instruct 2501 (24B params) fits at each quantization level on NVIDIA H100 80GB (80.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	9.4 GB	Low	C40
Q3_K_S	3	11.8 GB	Low	C41
NVFP4	4	13.4 GB	Medium	C41
Q4_K_M	4	14.6 GB	Medium	C41
Q5_K_M	5	17.3 GB	High	C41
Q6_K	6	19.7 GB	High	C42
Q8_0	8	25.7 GB	Very High	C43
F16Best for your GPU	16	49.2 GB	Maximum	C48