Can gemma 3 12b it run on AMD Instinct MI210 64GB?

YES — Runs Great

C47Usable

Estimated from fit model

gemma 3 12b it needs ~16.0 GB VRAM. AMD Instinct MI210 64GB has 64.0 GB. With Q4_K_M quantization, expect ~152 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 16.0 GB, 152.2 tok/s, Runs well

16.0 GB required64.0 GB available

25% VRAM used

Fit status

Runs well

Decode

152.2 tok/s

TTFT

1272 ms

Safe context

562K

Memory

16.0 GB / 64.0 GB

Memory breakdown

Weights7.3 GB

KV Cache1.4 GB

Runtime0.9 GB

Headroom6.4 GB

See how fast it feels

See how fast it feelsgemma 3 12b it on AMD Instinct MI210 64GB
1st promptCold start — includes initialization
>What is local AI inference?
Local AI inference means running an AI language model directly on your own hardware — your laptop, desktop, or server — instead of sending requests to a remote cloud API.

When you run inference locally the model weights are loaded into your GPU or unified memory. Each token you generate requires reading those weights from memory, so memory bandwidth is the main bottleneck for decode speed.

Key benefits of running locally:
  - Full privacy: your prompts never leave your machine
  - No per-token cost or rate limits
  - Works offline once the model is downloaded
  - Latency depends only on your hardware
2nd promptWarm — model ready, no init overhead
>How much VRAM do I need?
It depends on the model size and quantization level. A rough rule of thumb:

  Model size     Q4 (4-bit)    Q8 (8-bit)    FP16
  7B params      ~4.3 GB       ~7.5 GB       ~14 GB
  13B params     ~7.9 GB       ~13.9 GB      ~26 GB
  70B params     ~42.7 GB      ~74.9 GB      ~140 GB

Most people use 4-bit quantization (Q4_K_M) which gives 90-95% of full quality at a fraction of the memory. A 24 GB GPU can comfortably run most 7B-13B models.
Estimated: 152.2 tok/s decode · 1.3s TTFT (warm) · 380 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	152.2 tok/s	694 ms	562K
Coding	C	Runs well	152.2 tok/s	1272 ms	562K
Agentic Coding	C	Runs well	152.2 tok/s	1851 ms	562K
Reasoning	C	Runs well	152.2 tok/s	1504 ms	562K
RAG	C	Runs well	152.2 tok/s	2313 ms	562K

Quantization options

How gemma 3 12b it (12B params) fits at each quantization level on AMD Instinct MI210 64GB (64.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	4.7 GB	Low	C41
Q3_K_S	3	5.9 GB	Low	C41
NVFP4	4

Get started

Copy-paste commands to run gemma 3 12b it on your machine.

Run

lms load hf-maziyarpanahi--gemma-3-12b-it-gguf && lms server start

Upgrade options

Hardware that runs gemma 3 12b it well

Mac Studio M3 Ultra 96GBBudget pick

96 GB Unified (+32)

This setup is broadly balanced for this model.76.1 tok/s decode

~$3,999 MSRP

Frequently asked questions

Can AMD Instinct MI210 64GB run gemma 3 12b it?

Yes, AMD Instinct MI210 64GB can run gemma 3 12b it with a C grade (Runs well). Expected decode speed: 152.2 tok/s.

How much VRAM does gemma 3 12b it need?

gemma 3 12b it (12B parameters) requires approximately 16.0 GB of memory with Q4_K_M quantization.

What is the best quantization for gemma 3 12b it?

The recommended quantization for gemma 3 12b it is Q4_K_M, which balances quality and memory efficiency.

What speed will gemma 3 12b it run at on AMD Instinct MI210 64GB?

On AMD Instinct MI210 64GB, gemma 3 12b it achieves approximately 152.2 tokens per second decode speed with a time-to-first-token of 1272ms using Q4_K_M quantization.

Can AMD Instinct MI210 64GB run gemma 3 12b it for coding?

For coding workloads, gemma 3 12b it on AMD Instinct MI210 64GB receives a C grade with 152.2 tok/s and 562K context.

What context window can gemma 3 12b it use on AMD Instinct MI210 64GB?

On AMD Instinct MI210 64GB, gemma 3 12b it can safely use up to 562K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI210 64GB See all hardware for gemma 3 12b it

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