Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored needs ~48.6 GB VRAM. AMD Instinct MI250X 128GB has 128.0 GB. With Q4_K_M quantization, expect ~85 tok/s.
Operating mode
Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.
Current mode
Balanced
Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.
Select quantization to explore
Fit status
Runs well
Decode
85.2 tok/s
TTFT
2271 ms
Safe context
242K
Memory
48.6 GB / 128.0 GB
This setup is broadly balanced for this model.
No major red flags
This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.
| Workload | Grade | Fit | Decode | TTFT | Context |
|---|---|---|---|---|---|
| Chat | C | Runs well | 85.2 tok/s | 1239 ms | 242K |
| Coding | C | Runs well | 85.2 tok/s | 2271 ms | 242K |
| Agentic Coding | C | Runs well | 85.2 tok/s | 3303 ms | 242K |
| Reasoning | C | Runs well | 85.2 tok/s | 2684 ms | 242K |
| RAG | C | Runs well | 85.2 tok/s | 4129 ms | 242K |
How Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored (48B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).
| Quant | Bits | VRAM | Quality | Fit |
|---|---|---|---|---|
Q2_K | 2 | 18.7 GB | Low | D39 |
Q3_K_S | 3 | 23.5 GB | Low | D39 |
NVFP4 |
Copy-paste commands to run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored on your machine.
Run
lms load hf-davidau--qwen3-48b-a4b-savant-commander-distill-12x-closed-open-heretic-uncensored-gguf && lms server startYes, AMD Instinct MI250X 128GB can run Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored with a C grade (Runs well). Expected decode speed: 85.2 tok/s.
Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored (48B parameters) requires approximately 48.6 GB of memory with Q4_K_M quantization.
The recommended quantization for Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored is Q4_K_M, which balances quality and memory efficiency.
On AMD Instinct MI250X 128GB, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored achieves approximately 85.2 tokens per second decode speed with a time-to-first-token of 2271ms using Q4_K_M quantization.
For coding workloads, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored on AMD Instinct MI250X 128GB receives a C grade with 85.2 tok/s and 242K context.
Paste this snippet into any page to show a live fit card.
<iframe src="https://willitrunai.com/embed/hf-davidau--qwen3-48b-a4b-savant-commander-distill-12x-closed-open-heretic-uncensored-gguf-on-instinct-mi250x-128gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>
Preview:
| 4 |
26.9 GB |
| Medium |
| D40 |
Q4_K_M | 4 | 29.3 GB | Medium | C40 |
Q5_K_M | 5 | 34.6 GB | High | C41 |
Q6_K | 6 | 39.4 GB | High | C42 |
Q8_0 | 8 | 51.4 GB | Very High | C44 |
F16Best for your GPU | 16 | 98.4 GB | Maximum | C48 |
On AMD Instinct MI250X 128GB, Qwen3 48B A4B Savant Commander Distill 12X Closed Open Heretic Uncensored can safely use up to 242K tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.