Can Codestral 22B v0.1 run on AMD Instinct MI325X 256GB?

YES — Runs Great

C45Usable

Estimated from fit model

Codestral 22B v0.1 needs ~42.5 GB VRAM. AMD Instinct MI325X 256GB has 256.0 GB. With Q4_K_M quantization, expect ~308 tok/s.

Runtime: llama.cppCapacity: RoomyBandwidth: HighStack: StandardBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 42.5 GB, 308.0 tok/s, Runs well

42.5 GB required256.0 GB available

17% VRAM used

Fit status

Runs well

Decode

308.0 tok/s

TTFT

629 ms

Safe context

1.3M

Memory

42.5 GB / 256.0 GB

Memory breakdown

Weights13.4 GB

KV Cache2.6 GB

Runtime0.9 GB

Headroom25.6 GB

See how fast it feels

See how fast it feelsCodestral 22B v0.1 on AMD Instinct MI325X 256GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 308.0 tok/s decode · 629ms TTFT (warm) · 770 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	C	Runs well	308.0 tok/s	350 ms	1.3M
Coding	C	Runs well	308.0 tok/s	629 ms	1.3M
Agentic Coding	C	Runs well	308.0 tok/s	914 ms	1.3M
Reasoning	C	Runs well	308.0 tok/s	743 ms	1.3M
RAG	C	Runs well	308.0 tok/s	1143 ms	1.3M

Quantization options

How Codestral 22B v0.1 (22B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	8.6 GB	Low	D36
Q3_K_S	3	10.8 GB	Low	D36
NVFP4	4	12.3 GB	Medium	D36
Q4_K_M	4	13.4 GB	Medium	D36
Q5_K_M	5	15.8 GB	High	D36
Q6_K	6	18.0 GB	High	D37
Q8_0	8	23.5 GB	Very High	D37
F16Best for your GPU	16	45.1 GB	Maximum	D39

Get started

Copy-paste commands to run Codestral 22B v0.1 on your machine.

Run

lms load hf-bartowski--codestral-22b-v0-1-gguf && lms server start

Frequently asked questions

Can AMD Instinct MI325X 256GB run Codestral 22B v0.1?

Yes, AMD Instinct MI325X 256GB can run Codestral 22B v0.1 with a C grade (Runs well). Expected decode speed: 308.0 tok/s.

How much VRAM does Codestral 22B v0.1 need?

Codestral 22B v0.1 (22B parameters) requires approximately 42.5 GB of memory with Q4_K_M quantization.

What is the best quantization for Codestral 22B v0.1?

The recommended quantization for Codestral 22B v0.1 is Q4_K_M, which balances quality and memory efficiency.

What speed will Codestral 22B v0.1 run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Codestral 22B v0.1 achieves approximately 308.0 tokens per second decode speed with a time-to-first-token of 629ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Codestral 22B v0.1 for coding?

For coding workloads, Codestral 22B v0.1 on AMD Instinct MI325X 256GB receives a C grade with 308.0 tok/s and 1.3M context.

What context window can Codestral 22B v0.1 use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Codestral 22B v0.1 can safely use up to 1.3M tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.

See all results for AMD Instinct MI325X 256GB See all hardware for Codestral 22B v0.1

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<iframe src="https://willitrunai.com/embed/hf-bartowski--codestral-22b-v0-1-gguf-on-instinct-mi325x-256gb" width="400" height="180" frameborder="0" style="border:none;border-radius:12px;overflow:hidden;" title="Will It Run AI — fit result"></iframe>

Preview:

Workload

Grade

Fit

Decode

TTFT

Context

Chat

Runs well

308.0 tok/s

350 ms

1.3M

Coding

Runs well

308.0 tok/s

629 ms

1.3M

Agentic Coding

Runs well

308.0 tok/s

914 ms

1.3M

Reasoning

Runs well

308.0 tok/s

743 ms

1.3M

RAG

Runs well

308.0 tok/s

1143 ms

1.3M

Quantization options

How Codestral 22B v0.1 (22B params) fits at each quantization level on AMD Instinct MI325X 256GB (256.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	8.6 GB	Low	D36
Q3_K_S	3	10.8 GB	Low	D36
NVFP4	4	12.3 GB	Medium	D36
Q4_K_M	4	13.4 GB	Medium	D36
Q5_K_M	5	15.8 GB	High	D36
Q6_K	6	18.0 GB	High	D37
Q8_0	8	23.5 GB	Very High	D37
F16Best for your GPU	16	45.1 GB	Maximum	D39

Frequently asked questions

Can AMD Instinct MI325X 256GB run Codestral 22B v0.1?

Yes, AMD Instinct MI325X 256GB can run Codestral 22B v0.1 with a C grade (Runs well). Expected decode speed: 308.0 tok/s.

How much VRAM does Codestral 22B v0.1 need?

Codestral 22B v0.1 (22B parameters) requires approximately 42.5 GB of memory with Q4_K_M quantization.

What is the best quantization for Codestral 22B v0.1?

The recommended quantization for Codestral 22B v0.1 is Q4_K_M, which balances quality and memory efficiency.

What speed will Codestral 22B v0.1 run at on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Codestral 22B v0.1 achieves approximately 308.0 tokens per second decode speed with a time-to-first-token of 629ms using Q4_K_M quantization.

Can AMD Instinct MI325X 256GB run Codestral 22B v0.1 for coding?

For coding workloads, Codestral 22B v0.1 on AMD Instinct MI325X 256GB receives a C grade with 308.0 tok/s and 1.3M context.

What context window can Codestral 22B v0.1 use on AMD Instinct MI325X 256GB?

On AMD Instinct MI325X 256GB, Codestral 22B v0.1 can safely use up to 1.3M tokens of context. The model's official context limit is —, but available memory constrains the safe maximum.