Can Gemma 3 12B run on AMD Instinct MI100 32GB?

YES — Runs Great

A83Great

Estimated from fit model

Gemma 3 12B needs ~16.6 GB VRAM. AMD Instinct MI100 32GB has 32.0 GB. With Q4_K_M quantization, expect ~109 tok/s.

Runtime: OllamaCapacity: RoomyBandwidth: HighStack: BasicBottleneck: Balanced

Operating mode

Choose the run profile you care about

Interactive favors responsiveness, while light API and scale-out lean harder on serving readiness. The fit stays the same, but the recommendation lens changes.

Current mode

Balanced

Balanced for general local use. Keeps the ranking neutral across personal and serving workflows.

Capabilities:

Select quantization to explore

Q4_K_M (Medium quality) — 16.6 GB, 114.5 tok/s, Runs well

16.6 GB required32.0 GB available

52% VRAM used

Fit status

Runs well

Decode

114.5 tok/s

TTFT

1691 ms

Safe context

66K

Memory

16.6 GB / 32.0 GB

Memory breakdown

Weights7.3 GB

KV Cache4.9 GB

Runtime1.2 GB

Headroom3.2 GB

See how fast it feels

See how fast it feelsGemma 3 12B on AMD Instinct MI100 32GB
1st promptCold start — includes initialization
>Write a Python function to sort a list
Here's a Python function that sorts a list using quicksort:

def quicksort(arr):
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

# Example usage
numbers = [3, 6, 8, 10, 1, 2, 1]
print(quicksort(numbers))  # [1, 1, 2, 3, 6, 8, 10]

The algorithm picks a pivot, partitions the list into smaller, equal, and larger elements, then recursively sorts each partition and concatenates the results.
2nd promptWarm — model ready, no init overhead
>Now add type hints and a docstring
def quicksort(arr: list[int]) -> list[int]:
    """Sort a list using the quicksort algorithm.

    Args:
        arr: List of integers to sort.

    Returns:
        A new sorted list.
    """
    if len(arr) <= 1:
        return arr
    pivot = arr[len(arr) // 2]
    left   = [x for x in arr if x < pivot]
    middle = [x for x in arr if x == pivot]
    right  = [x for x in arr if x > pivot]
    return quicksort(left) + middle + quicksort(right)

Added type hints for the input and return type, plus a Google-style docstring.
Estimated: 114.5 tok/s decode · 1.7s TTFT (warm) · 286 tok/s prefill

What limits this setup

This setup is broadly balanced for this model.

No major red flags

This recommendation has enough memory headroom and acceptable estimated speed for the selected workload.

Best improvement path

Performance by workload

Workload	Grade	Fit	Decode	TTFT	Context
Chat	A	Runs well	114.5 tok/s	922 ms	66K
Coding	A	Runs well	109.0 tok/s	1775 ms	66K
Agentic Coding	S	Runs well	114.5 tok/s	2459 ms	66K
Reasoning	A	Runs well	114.5 tok/s	1998 ms	66K
RAG	S	Runs well	114.5 tok/s	3074 ms	66K

Quantization options

How Gemma 3 12B (12B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	4.7 GB	Low	A73
Q3_K_S	3	5.9 GB	Low	A74
NVFP4	4

Get started

Copy-paste commands to run Gemma 3 12B on your machine.

Run

ollama run gemma3:12b

Your hardware

More models your AMD Instinct MI100 32GB can run

Model	Params	Grade	Decode	Capabilities
Qwen3-Coder 30B A3B Instruct	30.5B	S	120.7 tok/s
Qwen 3.5 27B	27B	S	52.3 tok/s

Frequently asked questions

Can AMD Instinct MI100 32GB run Gemma 3 12B?

Yes, AMD Instinct MI100 32GB can run Gemma 3 12B with a A grade (Runs well). Expected decode speed: 109.0 tok/s.

How much VRAM does Gemma 3 12B need?

Gemma 3 12B (12B parameters) requires approximately 16.6 GB of memory with Q4_K_M quantization.

What is the best quantization for Gemma 3 12B?

The recommended quantization for Gemma 3 12B is Q4_K_M, which balances quality and memory efficiency.

What speed will Gemma 3 12B run at on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Gemma 3 12B achieves approximately 109.0 tokens per second decode speed with a time-to-first-token of 1775ms using Q4_K_M quantization.

Can AMD Instinct MI100 32GB run Gemma 3 12B for coding?

For coding workloads, Gemma 3 12B on AMD Instinct MI100 32GB receives a A grade with 109.0 tok/s and 66K context.

What context window can Gemma 3 12B use on AMD Instinct MI100 32GB?

On AMD Instinct MI100 32GB, Gemma 3 12B can safely use up to 66K tokens of context. The model's official context limit is 131K, but available memory constrains the safe maximum.

See all results for AMD Instinct MI100 32GB See all hardware for Gemma 3 12B

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